Dergiler / Turkish Journal of Medical Sciences / 2013 / Cilt: 43 - Sayı: 5

Association between maternal ghrelin levels and hyperemesis gravidarum

Sayfa
790–794
DOI
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Özet

To investigate serum levels of ghrelin in pregnant women as a potential early marker for hyperemesis gravidarum (HG). Materials and methods: A cross-sectional study was carried out at Fatih University Hospital. Included in the study were 35 women with HG and 31 pregnant women without HG as a control group. The groups were compared in terms of age, gravidity, body mass index (BMI), and fasting serum thyroid-stimulating hormone (TSH) and ghrelin levels. Results: Ghrelin levels of the patients with HG were found to be significantly lower than those in the control group (P = 0.03). No intergroup differences could be found in serum TSH or BMI values . Conclusion: Ghrelin might serve as a reliable marker in the etiopathogenesis of HG.

Abstract

To investigate serum levels of ghrelin in pregnant women as a potential early marker for hyperemesis gravidarum (HG). Materials and methods: A cross-sectional study was carried out at Fatih University Hospital. Included in the study were 35 women with HG and 31 pregnant women without HG as a control group. The groups were compared in terms of age, gravidity, body mass index (BMI), and fasting serum thyroid-stimulating hormone (TSH) and ghrelin levels. Results: Ghrelin levels of the patients with HG were found to be significantly lower than those in the control group (P = 0.03). No intergroup differences could be found in serum TSH or BMI values . Conclusion: Ghrelin might serve as a reliable marker in the etiopathogenesis of HG.

Anahtar kelimeler: Key words: Hyperemesis gravidarum, pregnancy, ghrelin, etiopathogenesis, thyroid-stimulating hormone, body mass index