Idiopathic granulomatous mastitis: an institutional experience

Özet

Objective: To study idiopathic granulomatous mastitis with respect to its various clinical features, etiologic factors,treatment modalities and complications.Material and methods: Retrospective study of all patients who were diagnosed with idiopathic granulomatous mastitis from 1st January 2006 to 31st December 2014 at Kasturba Hospital, Manipal, India (a tertiary care referral centre).The research was performed according to the World Medical Association Declaration of Helsinki. Informed consentwas taken from the patient before invasive procedures including surgery. Data was analysed using the StatisticalPackage for Social Sciences version 16.0 wherever appropriate.Results: 73 patients diagnosed with idiopathic granulomatous mastitis during the time period were included. Onepatient was a male (1.37%), rest were all females (98.63%). The mean age of presentation was 32.67 years (range 23to 66 years). 70 patients (95.89%) were parous females. Average duration since last childbirth was 4.6 years (range: 3months to 33 years). 8 patients (10.95%) were lactating. History of oral contraceptive pill use was present in 40 patients(54.79%). The right breast was affected in 44 patients (60.27%), and the left breast in 29 patients (39.73%). None of thepatients had bilateral disease. The most common symptom was a painless lump (61.64%). Rest of the patients (38.36%)presented with features of a breast abscess. 19 out of 39 FNACs done (48.72%) were positive for granulomatous mastitis.59 were primarily managed surgically (lumpectomy/ wide excision-33, incision & drainage-26). One patient was treatedprimarily with prednisolone. 13 patients did not receive specific treatment, and were only kept on regular follow-up.Patients managed with lumpectomy/ wide excision had the least rate of complications & recurrence (18.18%).Conclusion: Patients with idiopathic granulomatous mastitis can present with a wide variety of symptoms whichmimic other more common conditions. Surgical management in the form of wide excision appears to provide thebest long term outcome in patients with idiopathic granulomatous mastitis.