Minimally invasive thyroid anaplastic carcinoma with long survival

Özet

Anaplastic thyroid carcinoma is a highly lethal malignancy. Previously, only five cases of a noninvasive form ofanaplastic thyroid carcinoma with excellent prognosis were reported. We report a case of a 68-year-old man whopresented with a 3.8 cm thyroid nodule diagnosed by fine needle aspiration biopsy as poorly differentiated spindledand epithelial malignant cells. Lobectomy and isthmusectomy were performed, and the final diagnosis was microinvasive anaplastic thyroid carcinoma arising in a poorly differentiated carcinoma. The patient remains disease-freeafter six years, even after hemithyroidectomy and radiation treatment. Noninvasive/microinvasive anaplastic thyroid carcinoma appears to be a different disease entity from classical anaplastic thyroid carcinoma, with favorableprognosis and long disease-free survival.