Supraclavicular lymph node as the first presentation and late skin metastasis: an unusual clinical course for prostate cancer

Özet

Prostate cancer is the most common non-cutaneous malignancy and the second cause of cancer death inmen. Despite improvements in diagnostic methods, the primary diagnosis of a number of patients maystill be on metastatic stage. Cutaneous and supraclavicular lymph nodes are very rare metastatic sites forprostate cancer. In this report we present an extremely rare prostate cancer case diagnosed with supraclavicularlymph node and then developed cutaneous metastasis. A 64 year-old man was admitted to aninternal medicine outpatient clinic with supraclavicular lymph node and biopsy of lymph node showed anadenocarcinoma. After prostate cancer diagnosis, patient was treated with androgen deprivation therapy,docetaxel chemotherapy and abiraterone acetate, respectively. While abiraterone treatment, cutaneous metastasisdeveloped in inguinal area and diagnosis was confirmed by skin biopsy. In some cases, atypicalsymptoms may guide us to find disease with aggressive clinics. That’s why, physical rectal examination andprostate specific antigen measurements should be kept in mind for prostate cancer in male patients withsupraclavicular lymph node or atypical metastasis.