Impact of metabolic syndrome on pre- and postoperative parameters in patients undergoing a HoLEP surgery

Özet

Objective: We aimed to investigate the safety and success of the holmium laser enucleation of prostate(HoLEP) surgery in patients with metabolic syndrome (MS) versus those without MS who have similarprostate sizes.Material and methods: Data from 120 patients who underwent HoLEP by a single surgeon between November 2015 and January 2018 were prospectively analyzed. Group 1 (n=40) and Group 2 (n=80) consistedof patients with and without MS, respectively. Preoperative-and postoperative third month control variablesthat were compared between the groups included hemoglobin (Hb) level; International Prostate SymptomScore (IPSS); uroflowmetry parameters, such as maximum flow rate (Qmax) and average flow rate (Qave);post-voiding residue (PVR); voiding time (VT); and time to maximum flow rate (MVT).Results: For postoperative outcomes between the groups, only hospitalization time (HT) was significantamong IPSS, Qmax, Qave, PVR, VT, MVT, Hb decrease, and catheterization time (p=0.03). A multivariateanalysis showed that the triglyceride level positively correlated with HT among Group 1 patients (p=0.03).Perioperative outcomes, such as enucleated tissue weight, efficiency of enucleation, enucleation rate, efficiency of morcellation, enucleation time, morcellation time, total operation time, total laser energy, and laserefficiency, were compared as non-significant between the two groups (p>0.05).Conclusion: We found that HoLEP can be considered a safe and effective surgical treatment for patientswith MS.