The evaluation of predictive values of routine blood parameters for carotid artery disease in patients undergoing coronary artery bypass grafting

Özet

Objectives: In this study, we aimed to investigate the value of inflammatory biomarkers and atherogenicity index in predicting concomitantcarotid artery stenosis (CAS) in patients undergoing coronary artery bypass grafting (CABG).Patients and methods: A total of 257 patients (163 males, 94 females; mean age 59.2±8 years; range, 33 to 75 years) admitted to our clinicand scheduled for isolated CABG between January 2016 and January 2019 were retrospectively analyzed. The patients were divided into twogroups according to preoperative evaluation as those without significant CAS (Group 1, n=218) and those with CAS (≥50%) (Group 2, n=39).Results: The mean age was 55.9±7.9 in Group 1 and 65.7±9.4 in Group 2 (p<0.001). The mean platelet volume, neutrophil-to-lymphocyteratio, platelet-to-lymphocyte ratio, and triglyceride-to-high-density lipoprotein cholesterol (TG/HDL-C) ratio were significantly higher inGroup 2 (p=0.021, p=0.016, p=0.038, and p<0.001, respectively). In the multivariate analysis, age (odds ratio [OR]: 1.645, 95% confidenceinterval [CI]: 1.174-3.432, p=0.005), three-vessel/left main coronary artery disease (OR: 0.779, CI 95%: 0.576-0.912, p=0.021), andTG/HDL-C ratio (OR: 1.334, CI 95%: 1.190-2.785, p=0.015) were found to be independent predictors of concomitant significant CAS.Conclusion: Based on our study results, TG/HDL-C ratio, which can be measured from routine blood parameters, may be a useful predictorin predicting concomitant significant CAS in patients undergoing CABG.