Two sarcoidosis cases with lupus pernio and their clinical follow up

Özet

Lupus pernio, sarkoidosisin karakteristik cilt tutulum formuna verilen isimdir. Buna kemik kistleri,üst solunum yolu tutulumu ve kistik fibrozis eşlik edebilir. Sarkoidosisin kronik formudur ve kötü prognostik faktörlerinden biridir. Bu olgu sunumunda lupus pernio bulunan iki olgumuzu sunuyoruz. İlk olgumuzz, evre 2 sarkoidosis olup diğer sistemlerde tutulum yoktu. İkinci olgumuzda ise kemik kistleri, üst solunum yolu tutulumu ve sarkoidosisin nadir bulgular olan clubbing, ciltte hipopigmente lezyonlar bulunmaktaydı. İki olguda kronik seyirli olup biri 3 yd tedavi görmüş, diğeri ise 4 yıldır tedavi altındaydı.

Abstract

Lupus pernio is a characteristic cutenous involve¬ment forms of sarcoidosis. It can be accompanied by bone cysts, upper respiratory tract involvement and pulmonery fibrosis. It is a chronic form of sarcoidosis and it is one of the poor prognostic factors. In this case report two patients with lupus pernio were presented. In the first case with stage two sarcoidosis there was no other system involvement, whereas in the second case there was bone cysts, upper respiratory tract involvement, and also clubbing and hypopigmented skin lesions which are rare findings of sarcoidosis. In both of cases there was a chronic course and one of them was treated for three years and the other was under treatment for four years.