Saghkh ve Anemik Gebelerde Trombosit Parametreleri

Özet

Ama~: Gebeligin trombosit parametreleri iizerine yaptzgz etkiyi inceleyen bazz 0.05). Pearson korelasyon testi yapzldzgmda, trombosit sayzsz ve PCT ile hemoglobin, MCV ve MCH ile arasmda negatif yonlii korelasyon bulundu (p<0.05). MPVile hemoglobin, PDWile MCVve MCH arasmda negatif yonlii ve anlamlz bir ili~ki bulundu (p<0.05). Trombosit sayzsz ve PCT arasmda pozitif trombosit sayzsz ve MPV arasmda negatifyonde anlamlz bir ili~ki bulundu (p<0.001). Sonu<;: Bu <;alz~mada, anemik gebelerde ortalama trombosit sayzsz ve PCT degerinin anemik olmayan gebelere oranla daha yiiksek bulundugu gozlemlendi.

Abstract

Objective: In studies that examined the effect of pregnancy on platelet parameters, some studies have found no effect of pregnancy on platelet count, whereas some studies have claimed that the pregnancy have a reduction effect on platelet count. Although anemia is common during pregnancy as far as we could find there was no detailed study examining the relationship between anemia and changes in platelet count during pregnancy. Therefore, in this study it is aimed to evaluate platelet parameters in anemic pregnancies. Materials and methods: In this study, 247 pregnant women were included in the range of 18-32 weeks gestational age who were followed up in Obstetrics outpatient clinic of Department of Obstetrics and Gynecology of Adnan Menderes University School of Medicine. The results of complete blood count of pregnant women were retrospectively reviewed from hospital records. Cut-off value for anemia in the second trimester of pregnancy was taken as 10.5 g I dL. The pregnant women who were included in the study were divided into 2 groups taking into account the threshold value as the anemic group and the control group. Hematological parameters such as hemoglobin, hematocrit, mean corpuscular volume (MPV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red blood cell count, redcell distribution width (RDW), platelet count, platelet crit (PCT), mean platelet volume (MPV), platelet distribution width (PDW), leukocyte count were compared between the two groups. Pearson correlation analysis was performed for the correlation analysis. Results: There were 65 pregnant women in the anemic group and 182 pregnant women in the control group. When the hematologic parameters were compared between the anemic and the control group, hemoglobin, hematocrit, MCV and MCH were found lower in the anemic pregnant women than the control group (p<O.OOJ). The mean platelet count and mean value of PCT were found higher in the anemic pregnant group compared with the normal pregnant group (p<0.05). The mean value of MPV and PDW, however, did not differ between groups (p>0.05). When Pearson's correlation test was performed, a negative correlation was found between the platelet count and PCT and hemoglobin, MCV and MCH (p<O. 05). A significant and negative correlation was found between MPV and hemoglobin and between PDW and MCV and MCH (p <0.05). There was a positive correlation between platelet number and PCT, negative correlation between platelet number and MPV (p<O.OOJ). Conclusion: In this study, mean platelet count and the value of PCT were observed higher in the anemic pregnant women when compared with nonanemic pregnant women.