Retinal ven tıkanıklıklarında optik koherens tomografi bulgularının prognostik önemi

Prognostic significance of optical coherence tomographic findings in retinal vein occlusions

Özet

Amaç: Retinal ven tıkanıklıklarında sıklıkla saptanan optik kohorens tomografi (OKT) bulgularının prognostik değerinin araştırılması. Gereç ve Yöntem: Şubat 2010-Ekim 2013 tarihleri arasında hastanemiz Retina birimine başvuran ve semptomları son üç ay içinde gelişen; non-iskemik santral retinal ven tıkanıklığı (SRVO) veya retinal ven dal tıkanıklığı (BRVO) tanısı alan, 76 hastanın 76 gözü çalışmaya dahil edildi. Hastalar OKT bulgularına göre; en az bir tanesi >500 μm olmak üzere multiple kistik yapıların eşlik ettiği olgular (KMÖ), (Grup 1), 0.05). Sonuç: Santral retinal ven tıkanıklığı ve BRVOda OKT bulgularına ait tedavi öncesi değişik miktarlarda saptanan retina içi kistik ve retina altı sıvısı gibi anatomik değişiklikler ile görme keskinliği ve maküla kalınlığı açısından sonuç kazanımlar arasında belirgin fark saptanmamıştır.

Abstract

Purpose: To evaluate the prognostic value of common optical coherence tomographic (OCT) findings in retinal vein occlusions. Materials and Methods: Seventy-six eyes of 76 patients who applied our retina department between February 2010-October 2013, with the diagnosis of nonischemic central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO) that developed within 3 months, were enrolled in the study. Study population was classified into 3 subgroups with respect of OCT findings as follows: Cases with multiple retinal cystic lesions that at least one of which was greater than 500 microns (Group 1); cases with diffuse retinal edema that was consisted of multiple cystic lesions that were smaller than 250 microns (Group 2); and cases with intense subretinal fluid (Group 3). Results: In 32 cases (42.1%), CRVO was diagnosis, whereas BRVO was found in 44 cases (57.9%). Mean follow-up was found as 16.2±6.5 months (6-42 months), and 19.8±8.6 months (6-45 months) in patients, respectively. At the last follow-up visit, mean 14.2 ETDRS letters of gain (p:0.001) and mean -274 microns of CMT decrease (p:0.001) were found in patient with CRVO, additively, such scores were found as 16.2 letters (p:0.001) and -312 microns (p:0.001) in cases with BRVO. However no statistical significant difference was found among OCT-based classified subgroups in eyes with CRVO and BRVO (p>0.05). Conclusion: With respect of initial anatomical changes that could be detected via OCT, such as retinal cystic lesions and subretinal fluid formation, as well as changes in final visual acuity and macular thickness scores were not statistically dif- ferent in both CRVO and BRVO cases.