Dergiler / Molecular Imaging and Radionuclide Therapy / 2015 / Cilt: 24 - Sayı: 2
Prevalence of Helicobacter Pylori Infection in School and Pre-School Aged Children with C-14 Urea Breath Test and the Association with Familial and Environmental Factors
- Sayfa
- 66–70
- DOI
- —
Özet
Amaç: Okul çağı ve okul öncesi yaş grubu çocuklarda C-14 Üre Nefes Testi (ÜNT) ile Helicobacter pylori (Hp) enfeksiyonunun prevalansını araştırmak ve Türkiyede yaş ve sosyo-ekonomik faktörler ile ilişkisini ortaya çıkarmaktır. Yöntem: Hp enfeksiyonu varlığı ÜNT kullanılarak belirlendi. Daha öncesinde mide operasyon öyküsü olan, Hp eradikasyon tedavisi alan veya ÜNT değerleri şüpheli olan hastalar çalışmaya dahil edilmedi. Anamnez formu ile cinsiyet, yaş, boy, kilo, ABO/Rh kan grup tipi, ailede mide hastalığı öyküsü, evcil hayvan besleme ve demir eksiliği anemi tedavisi kullanımı öyküsü sorgulandı. Bulgular: Bu retrospektif çalışmaya 62si (%12,4) ≤6 yaş, 438si (%87,6) 7 ile 16 yaş aralığında olan 500 pediatrik hasta (179 erkek, 321 kız, ortalama yaş 10,7±4,3 yıl) dahil edildi. Hp 245 (%49) olguda pozitif bulundu. Okul öncesi yaş grubunda 21/62
Abstract
Objective: To investigate the prevalence of Helicobacter pylori (Hp) infection in pre-school and school age children with C-14 urea breath test, and to explore its association with age and socioeconomic factors in Turkey. Methods: Hp infection status was determined by using Urea Breath Test (UBT). Patients who had previous gastric surgery, Hp eradication treatment or equivocal UBT results were excluded. A questionnaire was administered to elicit information on gender, age, ABO/Rh blood group type, presence of gastric disease in the family, domestic animal in the household, and treatment for idiopathic Iron Deficiency Anemia (IDA). Results: This retrospective study included 500 pediatric patients (179 boys, 321 girls, mean age 10.7±4.3 years) of whom 62 (12.4%) were aged ≤6 years and 438 (87.6%) were aged 7 to 16 years. Helicobacter pylori (Hp) was positive in 245 (49%) cases. In the pre-school age group, 21/62 cases (34%) had positive UBT while in the school age group 224/438 children (51%) had positive UBT. A family history of dyspepsia and pet ownership were not associated with Hp positivity. Hp positive 76 (29.8%) children were on IDA treatment but this was not statistically significant. Conclusion: The Hp infection positivity rate was 49% in the pediatric age study group. The positivity rate was significantly lower at preschool age than school age, and it increased with age. There was no association with gender, ABO/Rh blood groups, presence of domestic pets, IDA, or history of gastric disease in the family.