Dergiler / Marmara Medical Journal / 2016 / Cilt: 29 - Sayı: 2

Immune mechanisms in chronic viral hepatitis

Sayfa
2–5
DOI
—

Özet

Hepatitis B virus (HBV) and Hepatitis C virus (HCV) arethe major causes of chronic liver inflammation worldwide.Although both viruses induce immune-mediated acute andchronic inflammatory liver diseases, the natural history andoutcome of HBV and HCV infections are different. Thisis because of both viruses and host features, like genetic,immunologic and environmental. Hereby, we present theimmune mechanisms and immunopathogenesis involved inchronic viral hepatitis.Keywords: HBV, HCV, Innate immunity, Adaptiveimmunity

Abstract

Hepatitis B virus (HBV) and Hepatitis C virus (HCV) arethe major causes of chronic liver inflammation worldwide.Although both viruses induce immune-mediated acute andchronic inflammatory liver diseases, the natural history andoutcome of HBV and HCV infections are different. Thisis because of both viruses and host features, like genetic,immunologic and environmental. Hereby, we present theimmune mechanisms and immunopathogenesis involved inchronic viral hepatitis.Keywords: HBV, HCV, Innate immunity, Adaptiveimmunity