Ventilator-associated pneumonia rates and distribution of causative microorganisms in the second stage intensive care unit

Özet

Ventilator-associated pneumonia (VAP) is the most important and common infection affecting patients ventilated with mechanical ventilators in intensive care units (ICU). VAP is defined as incubation-free pneumonia at 48-72 hours after endotracheal intubation. This retrospective study included adult patients (> 18 years old) who were hospitalized in our hospital’s General ICU between January 2018 and December 2019. According to the culture results, the patients were divided into two groups as VAP developing and non-VAP. The patients were evaluated in terms of causative agents, antibiotic susceptibilities and risk factors. Differences were reflected as significant at p<0.05. VAP developed in 43.7% of 87 patients included in the study. The mortality rate in VAP patients was 76.9%(29/38). While the hospitalization days of VAP patients were 34.39 ± 25.55, it was 8.35 ± 5.63 in non-VAP patients. Five different microorganisms causing VAP were detected in ICU. Pseudomonas aeruginosa (25%) was isolated most frequently. It was observed that susceptibility rates and resistance rates of microorganisms isolated to common antibiotics were low. VAP is a condition that affects the morbidity and mortality status of patients followed in ICU. Strategies should be developed to limit exposure to invasive mechanical ventilation, shorten length of ICU stay and rational antibiotic use.