Dergiler / Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering / 1985 / Cilt: 31
SYNTHESIS OF CERTAIN 4-METHYL-2-THIOURACIL DERIVATIVES TO BE TESTED AS ANTI-TUMOR OR ANTI-THYROID AGENTS
- Dergi
- Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering
- Sayı
- 1985 · Cilt: 31
- Sayfa
- 1–1
- DOI
- —
Abstract
Uracil and its 5-methyl derivative; thymine, are biologically öf great importance in fundamental metabolism. They derive their importance because certain of their derivatives are building blocks of RNA and DNA., 5-Fluorouıacil is particularly effective in the treatment of advan- ced carcinoma especially of the breast and the gastrointestinal tract; thiouracil, used in treating hyperthyroidism and angina pectoris.