Erythrocyte Anisocytosis as an Index of Severity inAcute Pancreatitis

Özet

Introduction: Most of the acute pancreatitis cases (AP) are mild; however, severe forms are risky for the patients, and those patients may benefit from early aggressive therapy. In this study, we investigated the predictivity of red cell distribution width (RDW ) as a potential biomarker of severity.Methods: In this study, a total of 123 patients with AP were classified high risk (Ranson score ≥3 or more, HR) and low-risk patients (Ranson score ≤3, LR). The patients were then investigated about the relationship of RDW to the severity of the disease and factors that affect prolonged hospital stay.Results: The median age and stay were 56 (IQR 46-71) years and four (IQR 3-5) days. Elevated levels of RDW corresponded to HR patients compared with the LR patients, 13.90 (IQR 13.40-14.78) vs 13.40 (IQR 13.00-14.00), p=0.001, respectively. Pro-longed hospital stay was related to higher Ranson scores and elevated lipase levels.Discussion and Conclusion: High lipase levels at hospitalization may be associated with a prolonged hospital stay. Elevated RDW levels may help in the prediction of high risk in acute pancreatitis patients at hospital admission.