Covid-19 ve Sindirim Sistemi

Özet

Çin’in Wuhan kentinde, Aralık 2019’da ilk defa görülen akut respiratory syndrome coronavirus 2 (SARS- CoV-2), corona hastalığı 2019 (Covid-19) olarak bilinen, tüm dünyada 100 den fazla ülkeyi ve 3,5 milyondan fazla insanı etkilemiştir. Önceleri yalnızca solunum yolu enfeksiyonu gibi görülse de, virüsün patogenezi anlaşıldıkça özellikle gastrointestinal sistem tutulumu ve fekal oral yayılımın da önemli olduğu görülmüştür. Bu makalede; Gastrointestinal sistem tutulumu mekanizması, gastrointestinal semptomlar, gastrointestinal sistem tutulumuna dair histopatolojik bulgular, karaciğer tutulumu, fekal-oral bulaş konuları tartışılacaktır.

Abstract

Acute respiratory syndrome caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan City of China, now known as coronavirus disease 2019(Covid-19), seen firstly in December 2019, has affected more than 100 countries and more than 3.5 million people worldwide. Although it was seen only as a respiratory infection in the begining, gastrointestinal system involvement and fecal- oral spread were considered as an important factor as the pathogenesis of the virus was understood. In this review article, the mechanism of the gastrointestinal system involvement, gastrointestinal symptoms, histopathological findings of gastrointestinal system involvement, liver functions, fecal-oral transmission will be discussed.