Dergiler / Turkish Journal of Chemistry / 2011 / Cilt: 35 - Sayı: 3

A near-infrared fluorescent sensor for H+ in aqueous solution and living cells

Sayfa
475–479
DOI
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Özet

A heptamethine cyanine-based sensor (1) was designed and synthesized by incorporating heptamethine cyanine fluorophore and methylpiperazine. Sensor 1 exhibited good response to the change of pH levels, and a large Stokes shift (>100 nm) was obtained. Fluorescent image experiments in living cells further demonstrated its potential applications in biological systems.

Abstract

A heptamethine cyanine-based sensor (1) was designed and synthesized by incorporating heptamethine cyanine fluorophore and methylpiperazine. Sensor 1 exhibited good response to the change of pH levels, and a large Stokes shift (>100 nm) was obtained. Fluorescent image experiments in living cells further demonstrated its potential applications in biological systems.

Anahtar kelimeler: Fluorescent image, heptamethine cyanine, pH sensor