Dergiler / Turkish Journal of Chemistry / 2012 / Cilt: 36 - Sayı: 1
Synthesis of a-aminonitriles catalyzed by montmorillonite K10 in the presence of dicationic phosphonium salt in water under ultrasonic effect
- Sayfa
- 101–109
- DOI
- —
Özet
The synthesis of a-aminonitriles was successfully accomplished by the 1-pot 3-component reaction of several aldehydes with (S)-a-phenylethylamine and sodium cyanide in water in the presence of montmorillonite K10 and dicationic phosphonium salt under ultrasonic effect with good yields and moderate diastereoselectivities.
Abstract
The synthesis of a-aminonitriles was successfully accomplished by the 1-pot 3-component reaction of several aldehydes with (S)-a-phenylethylamine and sodium cyanide in water in the presence of montmorillonite K10 and dicationic phosphonium salt under ultrasonic effect with good yields and moderate diastereoselectivities.