Dergiler / Turkish Journal of Chemistry / 2008 / Cilt: 32 - Sayı: 3

Efficient Synthesis of Imidazole Derivatives: An Important Synthon for the Preparation of Biologically Active Compounds

Sayfa
389–395
DOI
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Özet

4(5)-Chloro-imidazole-5(4)-carboxaldehyde derivatives are important precursors for the preparation of biologically active compounds. We developed a simple, novel, and efficient method for the synthesis of these compounds. The chemistry described is amenable to large-scale use and is flexible enough to allow the preparation of analogs.

Abstract

4(5)-Chloro-imidazole-5(4)-carboxaldehyde derivatives are important precursors for the preparation of biologically active compounds. We developed a simple, novel, and efficient method for the synthesis of these compounds. The chemistry described is amenable to large-scale use and is flexible enough to allow the preparation of analogs.

Anahtar kelimeler: Imidazole, N-chlorosuccinimide, chloroimidazole, chloroimidazole-carboxaldehyde