Dergiler / Turkish Journal of Chemistry / 2015 / Cilt: 39 - Sayı: 4

Microwave-assisted synthesis of novel 8-chloro-[1,2,4]triazolo[4,3-$a$]pyridine derivatives

Microwave-assisted synthesis of novel 8-chloro-[1,2,4]triazolo[4,3-a]pyridine derivatives

Sayfa
867–873
DOI
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Özet

A series of novel 1,2,4-triazolo[4,3-$a$]pyridine derivatives were synthesized from 2,3-dichloropyridine and hydrazine hydrate as starting materials by multistep reactions under microwave assistance, and their structures were characterized by $^{1}$H NMR, MS, and elemental analysis. This method provides several advantages such as high yields, facile work-up, and environmental friendliness.

Abstract

A series of novel 1,2,4-triazolo[4,3-$a$]pyridine derivatives were synthesized from 2,3-dichloropyridine and hydrazine hydrate as starting materials by multistep reactions under microwave assistance, and their structures were characterized by $^{1}$H NMR, MS, and elemental analysis. This method provides several advantages such as high yields, facile work-up, and environmental friendliness.

Anahtar kelimeler: 1, 2, 4-Triazolo[4, 3-$a$]pyridine, urea, microwave-assisted synthesis