Dergiler / Turkish Journal of Biology / 2008 / Cilt: 32 - Sayı: 2

Evaluation of Antioxidant and Antimicrobial Activity of Seaweed (Sargassum sp.) Extract: A Study on Inhibition of Glutathione-S-Transferase Activity

Sayfa
119–125
DOI
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Özet

In the present study, the free radical scavenging potentials (DPPH radical and hydroxyl radical), inhibition of lipid peroxidation, and glutathione-S-transferase and antimicrobial properties of Sargassum sp. extract were investigated. The tested extract exhibited a dose-dependent free radical scavenging action against DPPH radical and hydroxyl radical and antimicrobial activity. In addition, inhibition of lipid peroxidation and glutathione-S-transferase activities were also observed. The overall results have established that this seaweed could be used against several diseases and, in the food processing industry, to preserve foods.

Abstract

In the present study, the free radical scavenging potentials (DPPH radical and hydroxyl radical), inhibition of lipid peroxidation, and glutathione-S-transferase and antimicrobial properties of Sargassum sp. extract were investigated. The tested extract exhibited a dose-dependent free radical scavenging action against DPPH radical and hydroxyl radical and antimicrobial activity. In addition, inhibition of lipid peroxidation and glutathione-S-transferase activities were also observed. The overall results have established that this seaweed could be used against several diseases and, in the food processing industry, to preserve foods.

Anahtar kelimeler: Antimicrobial activity, free radical, glutathione-S-transferase, hydroxyl radical, lipid peroxidation