Dergiler / Turkish Journal of Veterinary and Animal Sciences / 2010 / Cilt: 34 - Sayı: 2
The effects of L-carnitine administration on energy metabolism in pregnant Halep (Damascus) goats
- Sayfa
- 163–171
- DOI
- —
Özet
The aim of this study was to determine the effects of parenteral administration of L-carnitine on some biochemical parameters in Halep (Damascus) goats during the last month of pregnancy. L-carnitine was administrated to goats in group I (n = 13) by subcutaneous injections once a week during the last month of the pregnancy. Physiologic salt solution was administered to goats in group II (n = 12) by the same route during the same period. Differences of glucose concentration between groups were not significant (P > 0.05). Serum b-hydroxybutyric acid (BHB) concentrations in both groups increased until parturition. However, differences between groups were not significant (P > 0.05). Concentration of serum NEFA (Non Esterified Fatty Acid) in group I was lower compared to group II 2 weeks before parturition (P < 0.05). Differences of serum triglyceride and cholesterol concentration between groups were not significant (P > 0.05). Level of glucose concentration in L-carnitine administered goats with twin kids was higher than the controls with twin kids in the 2nd (P < 0.01) and 3rd weeks (P < 0.05) before parturition. It was concluded that parenteral administration of L-carnitine might be a protective measure against pregnancy toxemia (ketosis) via increasing serum glucose concentration in goats with twin pregnancy.
Abstract
The aim of this study was to determine the effects of parenteral administration of L-carnitine on some biochemical parameters in Halep (Damascus) goats during the last month of pregnancy. L-carnitine was administrated to goats in group I (n = 13) by subcutaneous injections once a week during the last month of the pregnancy. Physiologic salt solution was administered to goats in group II (n = 12) by the same route during the same period. Differences of glucose concentration between groups were not significant (P > 0.05). Serum b-hydroxybutyric acid (BHB) concentrations in both groups increased until parturition. However, differences between groups were not significant (P > 0.05). Concentration of serum NEFA (Non Esterified Fatty Acid) in group I was lower compared to group II 2 weeks before parturition (P < 0.05). Differences of serum triglyceride and cholesterol concentration between groups were not significant (P > 0.05). Level of glucose concentration in L-carnitine administered goats with twin kids was higher than the controls with twin kids in the 2nd (P < 0.01) and 3rd weeks (P < 0.05) before parturition. It was concluded that parenteral administration of L-carnitine might be a protective measure against pregnancy toxemia (ketosis) via increasing serum glucose concentration in goats with twin pregnancy.