Atherosclerotic and metabolic effects of hypothyroidism due to chronic thyroiditis

Abstract

Hypothyroidism is the condition of decreased hormone production to provide the needs of peripheral tissues. Clinical symptoms may vary depending on patient's age, disease duration and thyroid hormone levels. Thyroid hormones are important determinants of basal metabolic rate and thyroid hormone status have a strong effect on different metabolic pathways (protein, carbohydrate, lipid) and atherosclerotic pathogenetic mechanisms.This review focuses on metabolic and atherosclerotic effects of hypothyroidism due to chronic (hashimoto) thyroiditis