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Dergiler / CURRENT THORACIC SURGERY / 2016 / Cilt: 1 Sayı: 1

Effect of tumor size on survival in pN0M0 non-small cell lung cancer patients

Gökhan Kocaman
Cabir Yüksel
Bülent Mustafa Yenigün
Mehmet Ali Sakallı
Durdu Karasoy
Murat Özkan
Serkan Enön
Ayten Kayı Cangır
Sayfa
12–15
Yayın Tarihi
2016-12-28
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

A tumor size of 4 cm was found to be the most suitable cut-off point for survival which may be of help in decision-making for adjuvant chemotherapy.

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Amaç & Hipotez:Background: Tumor size is one of the major prognostic determinants of non-small cell lung cancer (NSCLC).
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Temel Bulgular & Veri:In the present study, we evaluated the effect of tumor size on survival in pN0M0 NSCLC patients.
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Sonuç & Katkı:A tumor size of 4 cm was found to be the most suitable cut-off point for survival which may be of help in decision-making for adjuvant chemotherapy.
🔬Tür:Araştırma Makalesi
📍Kapsam:2013 Verileri
⚙️Değişkenler:Non-small cell lung cancer · tumor size · survival

Abstract

Background: Tumor size is one of the major prognostic determinants of non-small cell lung cancer (NSCLC). In the present study, we evaluated the effect of tumor size on survival in pN0M0 NSCLC patients. Materials and Methods: Between 1994 and 2013, 1975 NSCLC patients underwent surgery in our center. The study included 774 NSCLC patients with pathological stage N0M0, and these patients were divided into 8 groups according to tumor diameter, as follows, Group 1: 0-10 mm, Group 2: 11-20 mm, Group 3: 21-30 mm, Group 4: 31-40 mm, Group 5: 41-50 mm, Group 6: 51-60 mm, Group 7: 61-70 mm, and Group 8: > 70 mm. We aimed to evaluate the prognostic effect of tumor size on overall survival and to determine a cut-off point for tumor size. Results: The 5 year overall survival rate for groups 1 to 8 were 85.6%, 81.3%, 68.6%, 62.2%, 55%, 54.2%, 54.3%, and 45.6%, respectively. The mean follow-up time was 43.8 months. In multivariate analysis, age, tumor size, and surgical resection type had an independent prognostic value on survival. Conclusions : Tumor size is an independent prognostic factor for pN0M0 NSCLC patients. A tumor size of 4 cm was found to be the most suitable cut-off point for survival which may be of help in decision-making for adjuvant chemotherapy.

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Bu Makaleye Atıf Yap

Kocaman, G., Yüksel, C., Yenigün, B. M., Sakallı, M. A., Karasoy, D., Özkan, M., Enön, S., Cangır, A. K. (2016). Effect of tumor size on survival in pN0M0 non-small cell lung cancer patients. CURRENT THORACIC SURGERY, Cilt: 1 Sayı: 1, 12–15. https://ajindex.com/articles/984624

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Kaynakça (10)

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