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Dergiler / Bartın Üniversitesi Uluslararası Fen Bilimleri Dergisi / 2023 / Cilt: 6 Sayı: 1

SYNTHESIS AND FUNCTIONAL PROPERTIES OF DIPHENYLAMINE-CONTAINING SCHIFF BASES

Hasan Ufuk CELEBİOGLU
Ebru KÖROĞLU
Recep TAŞ
Sevilay GÜNAY
Yavuz ERDEN
Sayfa
40–55
Yayın Tarihi
2023-07-31
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In conclusion, the Schiff bases investigated in this study possess significant therapeutic potential.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Schiff bases have been widely researched in vitro for their antimicrobial, antitumor, antiviral, antineoplastic, and antioxidant properties, owing to their strong chelating ability.
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Temel Bulgular & Veri:Thus, this study aims to investigate the antibacterial, anticancer, and antioxidant effects of Schiff Bases N-methylene-N-phenylbenzenaminium and N-(5-oxopentylidene)-N-phenylbenzenaminium, as well as their impact on some properties of probiotic bacteria, Lactobacillus acidophilus and Lacticaseibacillus rhamnosus.
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Sonuç & Katkı:In conclusion, the Schiff bases investigated in this study possess significant therapeutic potential.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Antibacterial · anticancer · antioxidant

Abstract

Schiff bases have been widely researched in vitro for their antimicrobial, antitumor, antiviral, antineoplastic, and antioxidant properties, owing to their strong chelating ability. Probiotics refer to “live microorganisms that, when administered in adequate amounts, confer a health benefit on the host”. Thus, this study aims to investigate the antibacterial, anticancer, and antioxidant effects of Schiff Bases N-methylene-N-phenylbenzenaminium and N-(5-oxopentylidene)-N-phenylbenzenaminium, as well as their impact on some properties of probiotic bacteria, Lactobacillus acidophilus and Lacticaseibacillus rhamnosus. Results indicate that these Schiff bases promote the growth of probiotic bacteria while inhibiting pathogenic bacteria. They demonstrate potent antibacterial and antioxidant activities, and cytotoxicity assays reveal that both compounds exert a high degree of inhibition on human colon and breast cancer cells. Additionally, there is significant modulation in auto-aggregation and surface hydrophobicity of Lactobacillus acidophilus and Lacticaseibacillus rhamnosus. In conclusion, the Schiff bases investigated in this study possess significant therapeutic potential.

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Bu Makaleye Atıf Yap

CELEBİOGLU, H. U., KÖROĞLU, E., TAŞ, R., GÜNAY, S., ERDEN, Y. (2023). SYNTHESIS AND FUNCTIONAL PROPERTIES OF DIPHENYLAMINE-CONTAINING SCHIFF BASES. Bartın Üniversitesi Uluslararası Fen Bilimleri Dergisi, Cilt: 6 Sayı: 1, 40–55. https://ajindex.com/articles/957104

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Kaynakça (10)

  1. Abbo, H.S., Titinchi, S.J.J., Prasad, R. & Chand, S. (2005). Synthesis, characterization and study of polymeric iron (III) complexes with bidentate p-hydroxy Schiff bases as heterogeneous catalysts. Journal of Molecular Catalysis a-Chemical.;225(2), 225-232
  2. Abd-Elzaher, M.M., Labib, A.A., Mousa, H.A., Moustafa, S.A., Ali, M.M. & El-Rashedy, A.A. (2016). Synthesis, anticancer activity and molecular docking study of Schiff base complexes containing thiazole moiety. Beni-Suef University Journal of Basic and Applied Sciences.5(1), 85-96
  3. Alander, M., Satokari, R., Korpela, R., Saxelin, M., Vilpponen-Salmela, T. Mattila-Sandholm, T. & von Wright, A. (1999). Persistence of colonization of human colonic mucosa by a probiotic strain, Lactobacillus rhamnosus GG, after oral consumption. Appl. Environ. Microbiol., 65(1), 351-354
  4. Aly, A.A., Hassan, A.A., Makhlouf, M.M. & Bräse, S. (2020). Chemistry and biological activities of 1,2,4-triazolethiones—antiviral and anti-infective drugs. Molecules. 25(13), 30-36
  5. Arena, M.P., Capozzi, V., Spano, G. & Fiocco, D. (2017). The potential of lactic acid bacteria to colonize biotic and abiotic surfaces and the investigation of their interactions and mechanisms. Applied Microbiology and Biotechnology, 101(7), 2641-2657
  6. Bayani, M.A. & Azanza, M.P.V. (2005). Inhibition of Staphylococcus aureus by garlic and NaCl in broth systems. Food Science and Technology Research.11(2), 214-221
  7. Bjarnsholt, T., Jensen, P.O., Rasmussen, T.B., Christophersen, L., Calum, H., Hentzer, M., Hougen, H.P., Rygaard, J., Moser, C., Ebert, L., Hoiby, N. & Givskov, M. (2005). Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections. Microbiology-Sgm. 151, 3873-3880
  8. Brandt, A.L., Castillo, A., Harris, K.B., Keeton, J.T., Hardin, M.D. & Taylor, T.M. (2010). Inhibition of Listeria monocytogenes by Food Antimicrobials Applied Singly and in Combination. Journal of Food Science. 75(9), M557-M563
  9. Bringmann, G., Dreyer, M., Faber, J.H., Dalsgaard, P.W., Staerk, D., Jaroszewski, J.W., Ndangalasi, H., Mbago, F., Brun, R. & Christensen, S.B. (2004). Ancistrotanzanine C and related 5,1 '- and 7,3 '-coupled naphthylisoquinoline alkaloids from Ancistrocladus tanzaniensis. Journal of Natural Products. 67(5), 743-748
  10. Buck, B.L., Altermann, E., Svingerud, T. & Klaenhammer, T.R. (2005). Functional analysis of putative adhesion factors in Lactobacillus acidophilus NCFM. Applied and Environment