Dergiler / Journal of Basic and Clinical Health Sciences / 2023 / Cilt: 7 Sayı: 2

Investigation of Oral Mucositis Incidence and Risk Factors in Patients Receiving Chemotherapy

Sayfa
747–755
Yayın Tarihi
2023-05-31
DOI
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Therefore, patients should be followed up in the early period after chemotherapy.

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Amaç & Hipotez:Abstract Purpose: Oral mucositis is a common complication of cancer treatment that may negatively impact the patient’s cancer treatment outcome.
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Temel Bulgular & Veri:Material and Methods: This prospective cohort study included 150 participants undergoing outpatient cancer chemotherapy.
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Sonuç & Katkı:Therefore, patients should be followed up in the early period after chemotherapy.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:oral mucositis · chemotheraphy · mucositis

Abstract

Abstract Purpose: Oral mucositis is a common complication of cancer treatment that may negatively impact the patient’s cancer treatment outcome. This study was done to determine the incidence of oral mucositis development and risk factors in patients receiving chemotherapy. Material and Methods: This prospective cohort study included 150 participants undergoing outpatient cancer chemotherapy. To determine the development of oral mucositis, the participants were evaluated for the first course of chemotherapy (day 0) and the next course of chemotherapy treatment (day 14). ‘Patient Information Form’ and the World Health Organization’ Mucositis Grading Scale’ were used to collect data for the study. Descriptive statistics, chi-squared test, and logistic regression were used to analyze the results. Results: According to oral mucosal assessment, incidence of oral mucositis was 27.3%. The mean onset and the mean recovery of oral mucositis were 4.16 ± 2.13 days and 8.72 ± 2.32 days. The most common oral problems were mouth dryness (53.3%), dental caries (44%), and decreased sense of taste (32%). In the oral mucosal assessment performed on the 14th day, 9 patients were found to be grade 1. Patients with a history of mucositis (OR = 5.76, Cl = 2.33–14.24, p = 0.00) showed a significantly higher incidence of oral mucositis. Conclusion: In this study, the incidence of oral mucositis and risk factors that may affect the development of oral mucositis in patients receiving chemotherapy were investigated. Mucositis history was found as a risk factor in oral mucositis development. Early recovery of oral mucositis after chemotherapy was observed. Therefore, patients should be followed up in the early period after chemotherapy.

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Bu Makaleye Atıf Yap

GÖKTUNA, G., ARSLAN, G. G. (2023). Investigation of Oral Mucositis Incidence and Risk Factors in Patients Receiving Chemotherapy. Journal of Basic and Clinical Health Sciences, Cilt: 7 Sayı: 2, 747–755. https://ajindex.com/articles/939973

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Kaynakça (11)

  1. Villa A, Sonis ST. Mucositis: pathobiology and management. Curr Opin Oncol 2015;27(3):159-164.
  2. Elad S, Yarom N, Zadik Y, Kuten-Shorrer M, Sonis ST. The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies. CA Cancer J Clin 2022;72:57–77.
  3. Sonis ST. Precision medicine for risk prediction of oral complications of cancer therapy–The example of oral mucositis in patients receiving radiation therapy for cancers of the head and neck. Front Oral Health 2022;3-917860.
  4. Curra M, Valente Soares Junior LA, Martins MD, da Silva Santos PS. Chemotherapy protocols and incidence of oral mucositis. An integrative review. Einstein (São Paulo) 2018;16(1):1-9.
  5. Al-Ansari S, Zecha JA, Barasch A, de Lange J, Rozema FR, Raber-Durlacher JE. Oral mucositis induced by anticancer therapies. Current Oral Health Reports 2015;2(4):202-211.
  6. Wardill HR, Sonis ST, Blijlevens NMA, Van Sebille YZA, Ciorba MA, Loeffen EAH, et al. Prediction of mucositis risk secondary to cancer therapy: a systematic review of current evidence and call to action. Supportive Care in Cancer 2020;28(11):5059-5073.
  7. Çavuşoğlu H. Evidenced based nursing in the management of oral mucositis: Review. Turkiye Klinikleri J Med Sci 2007;27(3):398-406
  8. Shankar A, Roy S, Bhandari M, Rath GK, Biswas AS, Kanodia R, et al. Current trends in management of oral mucositis in cancer treatment. Asian Pac J Cancer Prev 2017;18(8):2019-2026.
  9. Cheng Fong KK, Lee V, Ho Li C, Goggins W, Thompson DR, Yuen HL, et al. Incidence and risk factors of oral mucositis in paediatric and adolescent patients undergoing chemotherapy. Oral Oncol 2011;47(3):153-162.
  10. Yang TJ, Oh JH, Son CH, Apte A, Deasy JO, Wu A, et al. Predictors of acute gastrointestinal toxicity during pelvic chemoradiotherapy in patients with rectal cancer. Gastrointest Cancer Res 2013;6(5-6):129-136
  11. Vokurka S, Bystricka E, Scudlova J, Mazur E, Visokaiova M, Vasilieva E, et al. The risk factors for oral mucositis and the effect of cryotherapy in patients after the BEAM and HD-L-PAM 200mg/m2 autologous hematopoietic stem cell transplantation. Eur J Oncol Nurs 201