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Dergiler / Health Sciences Quarterly / 2018 / Cilt: 2 - Sayı: 1

RESEARCH ON THE COMPOSITION AND CYTOTOXIC ACTIVITY OF PINUS BRUTIA GUM

Oytun ERTAŞ
Bengisu DÖNMEZ
Sibel KONYALIOGLU
Özlem SÖĞÜT
Sayfa
39–48
Yayın Tarihi
2018-01-31
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

After incubation of the saliva extract that including 10, 20, 50 µM caffeic acid in liver cancerous cells 1, 3, 6 hours, cell viability was observed.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Pinus Brutia Ten., traditionaly used as sugar regulator, antioxidant and antitumoral is consumed by chewing in Turkey.
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Temel Bulgular & Veri:The samples is stayed in artificial salvia at 37° C in ultrasonic bath for different time period and then determined by U-HPLC, PDA detector.
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Sonuç & Katkı:After incubation of the saliva extract that including 10, 20, 50 µM caffeic acid in liver cancerous cells 1, 3, 6 hours, cell viability was observed.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Pinus brutia gum · salvia · UPLC

Abstract

Pinus Brutia Ten., traditionaly used as sugar regulator, antioxidant and antitumoral is consumed by chewing in Turkey. The aim of the study is to investigate the components and the effect of the gum. The base of the study depends on the way of comsumption of the resin. For in-vitro analysis, artificial salvia is used. The samples is stayed in artificial salvia at 37° C in ultrasonic bath for different time period and then determined by U-HPLC, PDA detector. Three samples were prepared from each sample and three injections were made. Caffeic acid was investigate in the samples. The optimum waiting period is set at 5 hours, which is considered to be a possible period since the gum adheres to the tooth and is a hardly soluble substance. Considering the anticarcinogenic effect of caffeic acid, cytotoxic test was carried out on specimens which were kept in saliva for 24 hours acid. After incubation of the saliva extract that including 10, 20, 50 µM caffeic acid in liver cancerous cells 1, 3, 6 hours, cell viability was observed.

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Bu Makaleye Atıf Yap

ERTAŞ, O., DÖNMEZ, B., KONYALIOGLU, S., SÖĞÜT, Ö. (2018). RESEARCH ON THE COMPOSITION AND CYTOTOXIC ACTIVITY OF PINUS BRUTIA GUM. Health Sciences Quarterly, Cilt: 2 - Sayı: 1, 39–48. https://ajindex.com/articles/836680

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Kaynakça (13)

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