Dergiler / New Trends in Medicine Sciences / 2020 / Cilt: 1 - Sayı: 1

Diffusion tensor imaging of metastatic axillary lymph nodes

Sayfa
6–13
Yayın Tarihi
2020-06-15
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

ADC and FA showed a respectable diagnostic performance, especially the first one having a high negative PV and the second one relatively high specificity.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Objective: It was aimed to investigate whether the fractional anisotropy (FA) differs for the benign and metastatic axillary lymph nodes (LNs).
📊
Temel Bulgular & Veri:Material and Methods: 58 women with benign (n=33) and metastatic (n=25) axillary LNs who underwent diffusion weighted and tensor imaging with a 3T scanner were enrolled.
💡
Sonuç & Katkı:ADC and FA showed a respectable diagnostic performance, especially the first one having a high negative PV and the second one relatively high specificity.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Axilla · Apparent Diffusion Coefficient · Diffusion Tensor Imaging

Abstract

Objective: It was aimed to investigate whether the fractional anisotropy (FA) differs for the benign and metastatic axillary lymph nodes (LNs). Material and Methods: 58 women with benign (n=33) and metastatic (n=25) axillary LNs who underwent diffusion weighted and tensor imaging with a 3T scanner were enrolled. Apparent diffusion coefficient (ADC) and FA, cortex thickness, long and short axes were measured retrospectively and compared statistically. Observer reliabilities were also assessed in terms of intra and inter-reviewer variability. Results: Metastatic LNs showed significantly lower ADC and FA values and greater cortex thickness, long and short axes. ROC test showed the area under the curve values of 0.876 for ADC, 0.661 for FA and 0.960 for cortex thickness. Cortex thickness had excellent sensitivity, specificity, and accuracy. A cutoff value of 3.5 mm for cortex thickness had 92% sensitivity, 94% specificity, 92% positive predictive value (PV), 93% negative PV, and 93% accuracy. A cutoff value of 0.774x10-3 mm2/s for ADC had 84% sensitivity, 82% specificity, 79% positive PV, 90% negative PV, and 84% accuracy. A cutoff value of 0.423 x10-3 mm2/s for FA had 64% sensitivity, 76% specificity, 67% positive PV, 71% negative PV, and 71% accuracy. High intra- and inter-observer reliabilities were seen. Conclusion: Among the parameters assessed by our study, cortex thickness had superior accuracy. ADC and FA showed a respectable diagnostic performance, especially the first one having a high negative PV and the second one relatively high specificity.

🔖

Bu Makaleye Atıf Yap

DURUR-SUBASİ, İ., ALPER, F., TUNCEL, P., KARAMAN, A., ESDUR, V., DEMİRCİ, E., HEKİMOĞLU, B. (2020). Diffusion tensor imaging of metastatic axillary lymph nodes. New Trends in Medicine Sciences, Cilt: 1 - Sayı: 1, 6–13. https://ajindex.com/articles/793974

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (14)

  1. Fornasa F, Nesoti MV, Bovo C, et al. Diffusion-weighted magnetic resonance imaging in the characterization of axillary lymph nodes in patients with breast cancer. J Magn Reson Imaging 2012
  2. 858–64. Reference2. Silverstein MJ, Skinner KA, Lomis TJ. Predicting axillary nodal positivity in 2282 patients with breast carcinoma. World J Surg 2001
  3. 767–72. Reference3. Mansel RE, Fallowfield L, Kissin M et al. Randomized multicenter trial of sentinel node biopsy versus standard axillary treatment in operable breast cancer: the ALMANAC trial. J Natl Cancer Inst 2006
  4. 599–609. Reference4. Durur-Subasi I, Durur-Karakaya A, Alper F et al (2013) Breast lesions with high signal intensity on T1-weighted MR images. Jpn J Radiol 31:653–61. Reference5. Durur-Subasi I, Alper F, Akcay MN, et al. Magnetic resonance imaging findings of breast juvenile papillomatosis. Jpn J Radiol 2013
  5. 419–23. Reference6. Durur-Subasi I, Durur-Karakaya A, Karaman A, et al. Is the necrosis/wall ADC ratio useful for the differentiation of benign and malignant breast lesions? Br J Radiol 2017
  6. 20160803. Reference7. Durur-Subasi I, Durur-Karakaya A, Karaman A et al. Value of MRI sequences for prediction of invasive breast carcinoma size. J Med Imaging Radiat Oncol 2014
  7. 565–8. Reference8. Durur-Karakaya A, Seker M, Durur-Subasi I. Diffusion-Weighted Imaging in Ectopic Pregnancy: Ring of Restriction Sign. Br J Radiol 2017
  8. 20170528. Reference9. Pinker K, Helbich TH, Morris EA. The potential of multiparametric MRI of the breast. Br J Radiol 2017
  9. 20160715. Reference10. Guvenc I, Akay S, Ince S et al. Apparent diffusion coefficient value in invasive ductal carcinoma at 3.0 Tesla: is it correlated with prognostic factors? Br J Radiol 2016
  10. 20150614. Reference11. Cakir O, Arslan A, Inan N et al. Comparison of the diagnostic performances of diffusion parameters in diffusion weighted imaging and diffusion tensor imaging of breast lesions. Eur J Radiol 2013
  11. e801–6. Reference12. Eyal E, Shapiro-Feinberg M, Furman-Haran E et al. Parametric diffusion tensor imaging of the breast. Invest Radiol 2012
  12. 284–91. Reference13. Partridge SC, Ziadloo A, Murthy R et al. Diffusion tensor MRI: preliminary anisotropy measures and mapping of breast tumors. J Magn Reson Imaging 2010
  13. 339–47. Reference14. Baltzer PA, Schäfer A, Dietzel M et al. Diffusion tensor magnetic resonance imaging of the breast: a pilot study. Eur Radiol 2011
  14. 1–10. Reference15. Tagliafico A, Rescin