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Dergiler / Journal of Research in Veterinary Medicine / 2018 / Cilt: 37 Sayı: 2

Genotype frequency of FecXB (Belclare) mutation of BMP15 gene in Chios (Sakiz) sheep

Deniz DİNÇEL
Sena ARDIÇLI
Hale ŞAMLI
Faruk BALCI
Sayfa
87–91
Yayın Tarihi
2018-10-15
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Thus the effect of other major genes or regions/QTL’s should be investigated in future studies with a large number of animals.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Ovulation rate and litter size, varies between breeds or individulas who belong to the same breed, are evaluated as fertility traits.
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Temel Bulgular & Veri:Fecundity genes such as BMP15 regulate the fertility traits by increasing the ovulation rate due to the occuring mutations.
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Sonuç & Katkı:Thus the effect of other major genes or regions/QTL’s should be investigated in future studies with a large number of animals.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Sheep · fertiliy · mutation

Özet

Ovulation rate and litter size, varies between breeds or individulas who belong to the same breed, are evaluated as fertility traits. Fertility traits are important for economic values in animal breeding. However these traits exhibit only in females and they are determined in the later stages of lifes. Hence the genetic perspective is more effective way to confirm the fertility capacities early period of life time. Fecundity genes such as BMP15 regulate the fertility traits by increasing the ovulation rate due to the occuring mutations. Despite some prolific breed were investigated for FecXB mutation; the researches carried out to determine thatmutation in Chios sheep breed are limited. The objective of the current study was to estimate the the genotype frequencies of FecXB mutation of BMP15 gene in prolific Chios sheep. We investigated the FecXB mutation by PCR-RFLP method in Chios sheep (n=77). According to result, the investigated Chios breed was found monomorphic for FecXB mutation. All individuals were digested by DdeI restriction enzyme and showed wild-type genotype and did not carry FecXB mutation nin present study. In conclusion it’s thought that the high prolificacy in Chios sheep may be based on another region of BMP15 gene or different major gene. Thus the effect of other major genes or regions/QTL’s should be investigated in future studies with a large number of animals.

Abstract

Ovulation rate and litter size, varies between breeds or individulas who belong to the same breed, are evaluated as fertility traits. Fertility traits are important for economic values in animal breeding. However these traits exhibit only in females and they are determined in the later stages of lifes. Hence the genetic perspective is more effective way to confirm the fertility capacities early period of life time. Fecundity genes such as BMP15 regulate the fertility traits by increasing the ovulation rate due to the occuring mutations. Despite some prolific breed were investigated for FecXB mutation; the researches carried out to determine thatmutation in Chios sheep breed are limited. The objective of the current study was to estimate the the genotype frequencies of FecXB mutation of BMP15 gene in prolific Chios sheep. We investigated the FecXB mutation by PCR-RFLP method in Chios sheep (n=77). According to result, the investigated Chios breed was found monomorphic for FecXB mutation. All individuals were digested by DdeI restriction enzyme and showed wild-type genotype and did not carry FecXB mutation nin present study. In conclusion it’s thought that the high prolificacy in Chios sheep may be based on another region of BMP15 gene or different major gene. Thus the effect of other major genes or regions/QTL’s should be investigated in future studies with a large number of animals.

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Bu Makaleye Atıf Yap

DİNÇEL, D., ARDIÇLI, S., ŞAMLI, H., BALCI, F. (2018). Genotype frequency of FecXB (Belclare) mutation of BMP15 gene in Chios (Sakiz) sheep. Journal of Research in Veterinary Medicine, Cilt: 37 Sayı: 2, 87–91. https://ajindex.com/articles/778595

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Kaynakça (11)

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