Dergiler / International Archives of Medical Research / 2013 / Cilt: 5 - Sayı: 1

Does Microalbuminuria has Positive Predictive Value in Patients With Essential Hypertension for Renovascular Hypertension?

Sayfa
16–23
Yayın Tarihi
2013-06-01
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Conclusion: We suggest that microalbuminuria isn’t an indicator for renovascular hypertension in patients with essential hypertension.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Background: Renovascular disease is an important correctable cause of secondary hypertension.
📊
Temel Bulgular & Veri:Method: 330 essential hypertensive patients were enrolled to the study.
💡
Sonuç & Katkı:Conclusion: We suggest that microalbuminuria isn’t an indicator for renovascular hypertension in patients with essential hypertension.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Renovascular hypertension · essential hypertension · microalbuminuria

Abstract

Background: Renovascular disease is an important correctable cause of secondary hypertension. We aimed to research whether microalbuminuria might be an indicator for renovascular hypertension among the essential hypertensive patients. Method: 330 essential hypertensive patients were enrolled to the study. Patients were divided into 2 groups: group 1 (microalbuminuria) and group 2 (normoalbuminuria). Urine albumin concentrations were measured by nepholometry after 24-hour urine collection. All subjects were examined by renal duplex doppler ultrasonography and who had renal artery stenosis then MR angiography was performed. Results: Microalbuminuria was detected in 107 of 330 essential hypertensive patients (32.42%). Mean CrCl levels (108,14±19,83 vs 116,36±18,62, p=0,002) were significantly lower in the group of patients with microalbuminuria. 3/107 (2.80%) of the patients had renal artery stenosis in the group of patients with microalbuminuria and 8/223 (3.58%) of the patients had renal artery stenosis in the group of patients with normoalbuminuria. This study showed a sensitivity of 2.8%, specificity 96.41%, positive predictive value 27.27%, negative predictive value 67.40%. Conclusion: We suggest that microalbuminuria isn’t an indicator for renovascular hypertension in patients with essential hypertension.

🔖

Bu Makaleye Atıf Yap

YILMAZ, Z., ORUÇ, İ., YILDIRIM, Y., AYDIN, F. Y., AYDIN, E., KADİROGLU, A. K., YILMAZ, M. E. (2013). Does Microalbuminuria has Positive Predictive Value in Patients With Essential Hypertension for Renovascular Hypertension?. International Archives of Medical Research, Cilt: 5 - Sayı: 1, 16–23. https://ajindex.com/articles/764823

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (7)

  1. Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. (2005) Global burden of hypertension: analysis of worldwide data. Lancet, 365(9455):217–223.
  2. Safian RD, Textor SC. (2001) Renal-artery stenosis. N Engl J Med, 344:431. Davis BA, Crook JE, Vestal RE, Oates JA. (1979) Prevalence of renovascular hypertension in patients with grade III or IV hypertensive retinopathy. N Engl J Med, 301:1273. Mann SJ, Pickering TG. (1992) Detection of renovascular hypertension. State of the art, Ann Intern Med, 117:845. Vasbinder GB, Nelemans PJ, Kessels AG, Kroon AA, de Leeuw PW, van Engelshoven JM. (2001) Diagnostic tests for renal artery stenosis in patients suspected of having renovascular hypertension: a meta-analysis. Ann Intern Med.;135(6):401-11.
  3. Hirsch AT, Haskal ZJ, Hertzer NR, Bakal CW, Creager MA, Halperin JL et al. (2006) ACC/AHA 2005 Practice Guidelines for the management of patients with peripheral arterial disease Circulation, 113:e463. Mogensen CE. (1995) Microalbuminuria in prediction and prevention of diabetic nephropathy in insulin-dependent diabetes mellitus patients. J Diabetes Complicat, 9: 337–49.
  4. Newman DJ, Mattock MB, Dawnay AB, Kerry S, McGuire A, Yaqoob M et al. (2005) Systematic review on urine albumin testing for early detection of diabetic complications. Health Technol Assess. 9(30):160 -163. Parving HH, Mogensen CE, Jensen HA, Evrin PE. (1974) Increased urinary albumin-excretion rate in benign essential hypertension. Lancet, 1:1190–1192.
  5. Cerasola G, Cottone S, D'Ignoto G, Grasso L, Mangano MT, Carapelle E et al. (1989) Microalbuminuria as a predictor of cardiovascular damage in essential hypertension. J Hypertens Suppl, 7:S332-S333. Bigazzi R, Bianchi S, Campese VM, Baldari G. (1992) Prevalence of microalbuminuria in a large population of patients with mild to moderate essential hypertension. Nephron.61(1):94–7.
  6. Mogensen CE. (1984) Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes. N Engl J Med.310:356 –360. Hillege HL, Fidler V, Diercks GF, van Gilst WH, de Zeeuw D, van Veldhuisen DJ et al. (2002) Urinary albumin excretion predicts cardiovascular and noncardiovascular mortality in general population. Circulation.106:1777–1782.
  7. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr et al. (2003) The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA. 289(19):2560–2572. World Health Re