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Dergiler / International Archives of Medical Research / 2019 / Cilt: 11 - Sayı: 1

Klinefelter’s syndrome and social handicaps in Southeast of Turkey.

Diclehan ORAL
Selda ŞİMŞEK
Ayşegül TÜRKYILMAZ
İlyas YÜCEL
Selahattin TEKES
Mahmut BALKAN
Sayfa
17–25
Yayın Tarihi
2019-06-27
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Chromosomal analysis is strongly suggested particularly in those who suffer fertility problems.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:The term Klinefelter syndrome (KS) describes a group of chromosomal disorder in which there is at least one extra X chromosome to a normal male karyotype, 46,XY.
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Temel Bulgular & Veri:XXY aneuploidy is the most common disorder of sex chromosomes in humans, with prevalence of one in 500 males.
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Sonuç & Katkı:Chromosomal analysis is strongly suggested particularly in those who suffer fertility problems.
🔬Tür:Araştırma Makalesi
📍Kapsam:2010 Verileri
⚙️Değişkenler:Chromosomal abnormality · Male infertility

Abstract

The term Klinefelter syndrome (KS) describes a group of chromosomal disorder in which there is at least one extra X chromosome to a normal male karyotype, 46,XY. XXY aneuploidy is the most common disorder of sex chromosomes in humans, with prevalence of one in 500 males. Other sex chromosomal aneuploidies have also been described, although they are much less frequent, with 48,XXYY and 48,XXXY being present in 1 per 17,000 to 1 per 50,000 male birthsIn this study we aimed to evaluate the postnatally screened karyotype results in man who were referred diagnosis of Klinefelter syndrome between 1998 and 2010 in the city of Diyarbakir, Southeast Turkey.High resolution Giemsa banding chromosome analysis and/or fluorescence in situ hybridization were done males diagnosis of Klinefelter syndrome . A total of 552 cases were evaluated retrospectively.One hundred twenty out of 552 (21.74%) cases showed of Klinefelter syndrome.Genetic counseling was provided for the cases that received Klinefelter syndrome results. The rate of gonosomal chromosomal abnormalities was social problem in our region. Chromosomal analysis is strongly suggested particularly in those who suffer fertility problems.

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Bu Makaleye Atıf Yap

ORAL, D., ŞİMŞEK, S., TÜRKYILMAZ, A., YÜCEL, İ., TEKES, S., BALKAN, M. (2019). Klinefelter’s syndrome and social handicaps in Southeast of Turkey.. International Archives of Medical Research, Cilt: 11 - Sayı: 1, 17–25. https://ajindex.com/articles/764783

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Kaynakça (12)

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