Dergiler / Eurasian Journal of Critical Care / 2022 / Cilt: 4 - Sayı: 2

D-Dimer Levels and Prognostic Features in Pulmonary Embolism

Sayfa
58–62
Yayın Tarihi
2022-08-31
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Conclusion: In conclusion, even if pulmonary embolism is not detected in D-dimer positive cases, it is thought that these patients need further investigation, considering the frequency of serious conditions requiring clinical and intensive care unit admission.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Background: The aim of our study is to investigate the efficacy of D-dimer marker in patients who applied to the emergency department with a preliminary diagnosis of pulmonary embolism.
📊
Temel Bulgular & Veri:Materials and methods: This study was conducted retrospectively at Bursa Uludağ University Faculty of Medicine Hospital between January 2018 and December 2018.
💡
Sonuç & Katkı:Conclusion: In conclusion, even if pulmonary embolism is not detected in D-dimer positive cases, it is thought that these patients need further investigation, considering the frequency of serious conditions requiring clinical and intensive care unit admission.
🔬Tür:Araştırma Makalesi
📍Kapsam:2018 Verileri
⚙️Değişkenler:Emergency Medicine · Pulmonary Embolism · D-dimer

Abstract

Background: The aim of our study is to investigate the efficacy of D-dimer marker in patients who applied to the emergency department with a preliminary diagnosis of pulmonary embolism. Materials and methods: This study was conducted retrospectively at Bursa Uludağ University Faculty of Medicine Hospital between January 2018 and December 2018. Patients whose D-dimer levels were checked considering the preliminary diagnosis of pulmonary embolism were included in the study. Results: A total of 3411 patients were included in the study. In all patients, the diagnosis of PE was made by computed tomography pulmonary angiography. Examination of 1968 patients with (+) D-dimer revealed new diagnosis in 702 patients (35.67%). Pulmonary embolism was diagnosed in a total of 74 patients (10.54%) whereas the most common alternative diagnoses was 33.62% (n=236) pneumonia. On examination of 1443 patients with negative D-dimer levels, pulmonary embolism was diagnosed in 7 (3.14%) patients whereas the most common other diagnoses was 44.84% (n=100) Acute Coronary Syndrome. However, in the D-dimer positive patient group, the rate of newly diagnosed patients requiring clinical and intensive care hospitalization was found to be significantly higher. Conclusion: In conclusion, even if pulmonary embolism is not detected in D-dimer positive cases, it is thought that these patients need further investigation, considering the frequency of serious conditions requiring clinical and intensive care unit admission.

🔖

Bu Makaleye Atıf Yap

KURTOĞLU, B., ÇIKRIKLAR, H. İ., DURAK, V. A., OMAR, I., YILMAZ, A. M., CANDER, S. T. S., ARMAGAN, E. (2022). D-Dimer Levels and Prognostic Features in Pulmonary Embolism. Eurasian Journal of Critical Care, Cilt: 4 - Sayı: 2, 58–62. https://ajindex.com/articles/756047

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (14)

  1. Weitz JI, Fredenburgh JC, Eikelboom JW. A Test in context: D-Dimer. J Am Coll Cardiol 2017;70:2411-2420
  2. Keller K, Beule J, Balzer JO, Dippold W. D-Dimer and thrombus burden in acute pulmonary embolism. Am J Emerg Med 2018;36:1613-1618
  3. Bass AR, Fields KG, Goto R, Turissini G, Dey S, Russell LA. Clinical decision rules for pulmonary embolism in hospitalized patients: a systematic literature review and meta-analysis. Thromb Haemost 2017;117:2176-2185
  4. Wakai A, Gleeson A, Winter D. Role of fibrin D-dimer testing in emergency medicine. Emerg Med J 2003;20:319–325
  5. Geersing GJ, Janssen KJ, Oudega R, et al. Excluding venous thromboembolism using point of care D-dimer tests in outpatients: a diagnostic meta-analysis. BMJ 2009;339:b2990
  6. Farm M, Siddiqui AJ, Onelöv L, et al. Age-adjusted D-dimer cut-off leads to more efficient diagnosis of venous thromboembolism in the emergency department: a comparison of four assays. J Thromb Haemost 2018;16:866-875
  7. Carrier M, Righini M, Djurabi RK, et al. VIDAS D-dimer in combination with clinical pre-test probability to rule out pulmonary embolism. A systematic review of management outcome studies. Thromb Haemost 2009;101:886-892. 8. den Exter PL, van Es J, Klok FA, et al. Risk profile and clinical outcome of symptomatic subsegmental acute pulmonary embolism. Blood 2013;122:1144-1149
  8. Kabrhel C, Mark Courtney D, Camargo CA Jr, et al. Factors associated with positive D-dimer results in patients evaluated for pulmonary embolism. Acad Emerg Med 2010;17:589-597
  9. Righini M, Van Es J, Den Exter PL, et al. Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: the ADJUST-PE study. JAMA 2014;311:1117-1124
  10. Lippi G, Bonfanti L, Saccenti C, Cervellin G. Causes of elevated D-dimer in patients admitted to a large urban emergency department. Eur J Intern Med 2014;25:45-48
  11. Akbaş SH, Can M, Kılıçarslan I, Özdem S, Çete Y, Gültekin M. Acil Servise Başvuran Yüksek D-dimer Düzeyli Hastalarda Tanı Dağılımı ve D-dimer Düzeylerinin Hastaneye Yatış ve Ölüm Oranları ile İlişkisi. Turk J Emerg Med 2004;4:149-154
  12. Falanga A, Russo L, Milesi V, Vignoli A. Mechanisms and risk factors of thrombosis in cancer. Crit Rev Oncol Hematol. 2017;118:79-83
  13. Levitan N, Dowlati A, Remick SC, et al. Rates of initial and recurrent thromboembolic disease among patients with malignancy versus those without malignancy. Risk analysis using Medicare claims data. Medicine 1999;78:285-291
  14. Wang S, Zimmermann S,