KaydedilenlerDerginizi ekleyin

Dergiler / International Journal of Secondary Metabolite / 2022 / Cilt: 9 - Sayı: 1

Comparison of three different protocols of alkaloid extraction from Glaucium corniculatum plant

Fatma Gonca KOÇANCI
Serap NİĞDELİOĞLU DOLANBAY
Belma ASLIM
Sayfa
43–51
Yayın Tarihi
2022-03-10
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Thus, a new modified alkaloid extraction protocol was established, which is better than the other protocol.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Alkaloids, plant secondary metabolites, have a wide variety of biological effects.
📊
Temel Bulgular & Veri:For this reason, the extraction of alkaloids from plants is of strategic importance.
💡
Sonuç & Katkı:Thus, a new modified alkaloid extraction protocol was established, which is better than the other protocol.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alkaloid · Extraction · Glaucium corniculatum

Özet

Alkaloids, plant secondary metabolites, have a wide variety of biological effects. For this reason, the extraction of alkaloids from plants is of strategic importance. Different extraction protocols for the extraction of alkaloids from plants have been described by many authors. The objective of this study was to compare the efficacy of three different protocols for the extraction of alkaloids from Glaucium corniculatum. This article compares the Soxhlet and ultrasonication protocol, used in previous studies, to a modified Soxhlet protocol. While the alkaloid amount in the extract was determined by the spectrophotometric method, the qualitative estimation of the compounds in the extract was determined by Gas chromatograph-Mass spectrometer (GC-MS). The alkaloid amount and diversity in the extract, obtained through the recommended modified Soxhlet protocol, were higher than that of any extract obtained through other protocols. Thus, a new modified alkaloid extraction protocol was established, which is better than the other protocol.

Abstract

Alkaloids, plant secondary metabolites, have a wide variety of biological effects. For this reason, the extraction of alkaloids from plants is of strategic importance. Different extraction protocols for the extraction of alkaloids from plants have been described by many authors. The objective of this study was to compare the efficacy of three different protocols for the extraction of alkaloids from Glaucium corniculatum. This article compares the Soxhlet and ultrasonication protocol, used in previous studies, to a modified Soxhlet protocol. While the alkaloid amount in the extract was determined by the spectrophotometric method, the qualitative estimation of the compounds in the extract was determined by Gas chromatograph-Mass spectrometer (GC-MS). The alkaloid amount and diversity in the extract, obtained through the recommended modified Soxhlet protocol, were higher than that of any extract obtained through other protocols. Thus, a new modified alkaloid extraction protocol was established, which is better than the other protocol.

🔖

Bu Makaleye Atıf Yap

KOÇANCI, F. G., DOLANBAY, S. N., ASLIM, B. (2022). Comparison of three different protocols of alkaloid extraction from Glaucium corniculatum plant. International Journal of Secondary Metabolite, Cilt: 9 - Sayı: 1, 43–51. https://ajindex.com/articles/672852

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (10)

  1. Almousawi, U.M.N., & Alwan, A.A. (2017). The significance of opium alkaloids in the classification of Papaveraceae in Iraq. Journal of Pharmacognosy and Phytochemistry, 6(1), 430-437.
  2. Amirkia, V., & Heinrich, M. (2014). Alkaloids as drug leads A predictive structural and biodiversity based analysis. Phytochemistry Letters, 10. https://cyberleninka.org/article/n/1019139
  3. Chaves, K.M.S., M. Feitosa, C., & da S. Araújo, L. (2016). Alkaloids Pharmacological Activities-Prospects for the Development of Phytopharmaceuticals for Neurodegenerative Diseases. Current Pharmaceutical Biotechnology, 17(7), 629-635.
  4. Cushnie, T.P.T., Cushnie, B., & Lamb, A.J. (2014). Alkaloids: An overview of their antibacterial, antibiotic-enhancing and antivirulence activities. International Journal of Antimicrobial Agents, 44(5), 377-386. https://doi.org/10.1016/j.ijantimicag.2014.06.001
  5. Demaggio, A.E., & Lott, J.A. (1964). Application of Ultrasound for Increasing Alkaloid Yield from Datura Stramonium. Journal of Pharmaceutical Sciences, 53(8), 945-949. https://doi.org/10.1002/jps.2600530822
  6. Desgrouas, C., Baghdikian, B., Mabrouki, F., Bory, S., Taudon, N., Parzy, D., & Ollivier, E. (2014). Rapid and green extraction, assisted by microwave and ultrasound of cepharanthine from Stephania rotunda Lour. Separation and Purification Technology, 123, 9-14. https://doi.org/10.1016/j.seppur.2013.12.016
  7. Dittbrenner A. (2009). Morphologische, phytochemische und molekulare Untersuchungen zur intraspezifi schen Diversität von Schlafmohn (Papaver somniferum L.). [PhD Thesis, Martin Luther University]. Halle-Wittenberg, Germany. http://dx.doi.org/10.25673/502
  8. Doncheva, T., Kostova, N., Yordanova, G., Saadi, H., Akrib, F., Dimitrov, D., & Philipov, S. (2014). Comparison of alkaloid profile from Glaucium corniculatum (Papaveraceae) of Algerian and Bulgarian origin. Biochemical Systematics and Ecology, 56, 278-280. https://www.cabdirect.org/cabdirect/abstract/20143390676
  9. Hesse, M. (2002). Alkaloids: Nature’s Curse Or Blessing? John Wiley & Sons. Järnberg, U., Asplund, L., & Jakobsson, E. (1994). Gas chromatographic retention behaviour of polychlorinated naphthalenes on non-polar, polarizable, polar and smectic capillary columns. Journal of Chromatography A, 683(2), 385-396. https://doi.org/10.1016/0021-9673(94)00515-X
  10. Jimoh, F., Adedapo, A., Aliero, A., & Afolayan, A. (2010). Polyphenolic and biological activities of leaves extracts of Argemone subfusiformis (Papaveraceae) and Urtica urens (Urticaceae).