Dergiler / Gaziosmanpaşa Üniversitesi Ziraat Fakültesi Dergisi / 2022 / Cilt: 39 - Sayı: 2

Bioinformatical Evaluation of PPARA and PPARG Candidate Genes for Milk Quality Characteristics in Turkish Saanen Goats

Sayfa
77–84
Yayın Tarihi
2022-11-06
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Single nucleotide polymorphisms were detected in the exons and introns of the relevant gene variants, however, these polymorphisms did not have a statistically significant effect on quality parameters (p>0.05).

📌 3 Maddede Bu Makale

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Amaç & Hipotez:In this study, genetic information obtained in terms of milk yield and milk quality characteristics was used in order to increase the accuracy of breeding selection of Turkish Saanen goats.
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Temel Bulgular & Veri:For this purpose, DNA sequencing of PPARG and PPARA genes from Turkish Saanen goats were compared with the sequences in gene databases and single nucleotide polymorphisms were examined.
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Sonuç & Katkı:Single nucleotide polymorphisms were detected in the exons and introns of the relevant gene variants, however, these polymorphisms did not have a statistically significant effect on quality parameters (p>0.05).
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Bioinformatics · Candidate genes · PPARA

Abstract

In this study, genetic information obtained in terms of milk yield and milk quality characteristics was used in order to increase the accuracy of breeding selection of Turkish Saanen goats. For this purpose, DNA sequencing of PPARG and PPARA genes from Turkish Saanen goats were compared with the sequences in gene databases and single nucleotide polymorphisms were examined. A relationship was found between some quality parameters (fat, protein and somatic cell count) of milk measurements of Turkish Saanen goats and PPARA and PPARG gene variants. Single nucleotide polymorphisms were detected in the exons and introns of the relevant gene variants, however, these polymorphisms did not have a statistically significant effect on quality parameters (p>0.05).

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Bu Makaleye Atıf Yap

ATAÇ, F. E., GEVREKÇİ, Y., TAKMA, Ç., AKKAYA, F., YILMAZ, M. C., AYYILMAZ, T., YEĞENOĞLU, E. D. (2022). Bioinformatical Evaluation of PPARA and PPARG Candidate Genes for Milk Quality Characteristics in Turkish Saanen Goats. Gaziosmanpaşa Üniversitesi Ziraat Fakültesi Dergisi, Cilt: 39 - Sayı: 2, 77–84. https://ajindex.com/articles/650799

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Kaynakça (7)

  1. Abousoliman, I., Reyer, H., Oster, M., Murani, E., Mohamed I., & Wimmers, K. (2021). Genome-Wide SNP Analysis for Milk Performance Traits in Indigenous Sheep: A Case Study in the Egyptian Barki Sheep. Animals, 11(6):1671. https://doi.org/10.3390/ani11061671
  2. Ataç, F.E., Takma, Ç., Gevrekçi, Y., Yeğenoğlu, E.D., & Örgel, S. (2018). Hair Goat Breeding in Ecological Environment and Products: A Review. International Echology 2018
  3. Symposium, P:1058, 19-23 June 2018, Kastamonu Turkey. www.ecology2018.com Benjelloun, B., Alberto, F. J., Streeter, I., Boyer, F., Coissac, E., Stucki, S., Mohammed,B., Mustapha, I., Mouad, C., Abdelmajid, B., Kevin, B., Adriana, A., Stefan, E., Abdelkader, C., Laura, C., Paul, F., Stephane, J., Pierre, T., Farnçois, P., & Nextgen, C. (2015). Characterizing neutral genomic diversity and selection signatures in indigenous populations of Moroccan goats (Capra hircus) using WGS data. Frontiers in Genetics, 6:107. doi: 10.3389/fgene.2015.00107. Bentley150 Operator’s Manual. (1999). A guide for installation, operation, and maintenance. Bentley Instruments, Inc. Chaska, Minnesota, USA. Bionaz, M., Hausman, G.J., & Mandard, S. (2013). Physiological and nutritional roles of PPAR across species. PPAR Research, 1-3. D’Agostino, G., LaRana, G., Russo, R., Sasso, O., Iacono, A., & Esposito, E. (2007). Acute intracerebroventricular administration of palmitoylethanolamide, an endogenous peroxisome proliferator-activated receptor-alpha agonist, modulates carrageenan- induced paw edema in mice. Journal of Pharmacology and Experimental Therapeutics, 322:1137-43.
  4. Ebrahimi-Mamaeghani, M., Mohammadi, S., Arefhosseini, S. R., Fallah, P., & Bazi, Z. (2015). Adiponectin as a potential biomarker of vascular disease. Vascular Health and Risk Management, 11: 55-70.
  5. Fan, Y. Y., Sen Zan, l., Fu, C. Z., Tian, W.Q., Wang, H. B., Liu, Y. Y., & Xin, Y. P. (2011).Three novel SNPs in the coding region of PPARγ gene and their associations with meat quality traits in cattle. Molecular Biology Reports, 38 (2011), pp. 131-137.
  6. Ferreira, L., Soaresa, M.A.M., Rodrigues, M.T., de Araujoc, J.L.S., Melod, A.L.P., Gasparinoe, E., & Garciaa, O.S.R. (2020). UCP2 and PPARG gene polymorphisms and their association with milk yield and composition traits in goats. Small Ruminant Research Volume, 192, November 2020, 106210 Haenlein, G.F.W. (2007). About the evolution of goat and sheep milk production. Small Ruminant Research, 68: 3-6.
  7. Hou, J.X., An, X.P., Song, Y.X., Wang, J.G., Ma, T