KaydedilenlerDerginizi ekleyin

Dergiler / European Archives of Medical Research / 2019 / Cilt: 35 - Sayı: 2

Serum Neuron Specific Enolase and S-100B Levels in Hemodialysis and Peritoneal Dialysis Patients

Alper AZAK
Murat DURANAY
Medine ALPDEMİR
Mehmet Fatih ALPDEMİR
Doğan YÜCEL
Mehmet ŞENEŞ
Oğuzhan ÖZCAN
Sayfa
83–87
Yayın Tarihi
2022-11-05
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

S-100B and NSE levelswere higher after HD compared to before HD (p

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Objective: Neuron-specific enolase (NSE) and S-100B are brain-derived proteins, and their levels increase in brain injury.
📊
Temel Bulgular & Veri:The aim of the study wasto determine serum S-100B and NSE levels in patients with end-stage renal disease undergoing hemodialysis (HD) and peritoneal dialysis (PD) and todemonsrate how these levels were affected by the type of dialysis applied.Methods: The study group consisted of age- and gender-matched 20 patients undergoing HD, 26 patients undergoing continuous ambulatory PD(CAPD) and 21 healthy controls.
💡
Sonuç & Katkı:S-100B and NSE levelswere higher after HD compared to before HD (p
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Objective: Neuron-specific enolase (NSE) and S-100B are brain-derived proteins, and their levels increase in brain injury. The aim of the study wasto determine serum S-100B and NSE levels in patients with end-stage renal disease undergoing hemodialysis (HD) and peritoneal dialysis (PD) and todemonsrate how these levels were affected by the type of dialysis applied.Methods: The study group consisted of age- and gender-matched 20 patients undergoing HD, 26 patients undergoing continuous ambulatory PD(CAPD) and 21 healthy controls. Blood samples were obtained before and after dialysis in the HD patient group, and fasting blood samples wereobtained in the CAPD and control groups. The routine biochemical parameters were measured within two hours from all serum samples. Theremaining serum samples were stored at -80 °C until the day of analysis of the S-100B and NSE assays. Serum S-100B and NSE levels were measuredby chemiluminescence immunoassay method. Routine biochemistry tests were measured by colorimetric method using a biochemistry analyzer.Results: Serum S-100B (0.11±0.06 ng/mL in HD, 0.13±0.09 ng/mL in CAPD and 0.05±0.03 ng/mL in controls) and NSE (12.7±5.99 ng/mL in HD,9.26±5.52 ng/mL in CAPD and 6.82±2.36 ng/mL in controls) levels were higher in HD and CAPD groups compared to controls. S-100B and NSE levelswere higher after HD compared to before HD (p

🔖

Bu Makaleye Atıf Yap

AZAK, A., DURANAY, M., ALPDEMİR, M., ALPDEMİR, M. F., YÜCEL, D., ŞENEŞ, M., ÖZCAN, O. (2022). Serum Neuron Specific Enolase and S-100B Levels in Hemodialysis and Peritoneal Dialysis Patients. European Archives of Medical Research, Cilt: 35 - Sayı: 2, 83–87. https://ajindex.com/articles/650417

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (14)

  1. Kunihara T, Shiiya N, Bin L, Yasuda K. Arterio-jugular differences in serum S-100 beta proteins in patients receiving selective cerebral perfusion. Surg Today 2006;36:6-11
  2. Herrmann M, Ebert AD, Galazky I, Wunderlich MT, Kunz WS, Holzmann D. Neurobehavioral outcome prediction after cardiac surgery: role of neurobiochemical markers of damage to neuronal and glial brain tissue. Stroke 2000;31:645-50
  3. Mielck F, Ziarkowski A, Hanekop G, Armstrong VW, Hilgers R, Weyland A, et al. Cerebral inflammatory response during and after cardiac surgery. Eur J Anaesthesiol 2005;22:347-52
  4. Infante JR, Martinez A, Ochoa J, Cañadillas F, Torres-Avisbal M, Vallejo JA, et al. Cerebrospinalfluid S-100 protein levels in neurological pathologies. J Physiol Biochem 2003;59:255-61
  5. Heizmann CW, Fritz G, Schafer BW. S100 proteins: structure, functions and pathology. Front Biosci 2002;7:1356-68
  6. Jonsson H, Johnsson P, Alling C, Westaby S, Blomquist S. Significance of serum S100 release after coronary artery bypass grafting. Ann Thorac Surg 1998;65:1639-44
  7. Rothoerl RD, Brawanski A, Woertgen C. S-100B protein serum levels after controlled cortical impact injury in the rat. Acta Neurochir (Wien) 2000;142:199-203
  8. Kilminster S, Treasure T, McMillan T, Holt DW. Neuropsychological change and S-100 protein release in 130 unselected patients undergoing cardiac surgery. Stroke 1999;30:1869-74
  9. Steinberg R, Gueniau C, Scarna H, Keller A, Worcel M, Pujol JF. Experimental brain ischemia: Neuron-specific enolase level in cerebrospinal fluid as an index of neuronal damage. J Neurochem 1984;43:19-24
  10. Schoerkhuber W, Kittler H, Sterz F, Behringer W, Holzer M, Frossard M, et al. Time course of serum neuron-specific enolase. A predictor of neurological outcome in patients resuscitated from cardiac arrest. Stroke 1999;30:1598- 603
  11. Herrmann M, Ebert AD, Tober D, Hann J, Huth C. A contrastive analysis of release patterns of biochemical markers of brain damage after coronary artery bypass grafting and valve replacement and their association with the neurobehavioral outcome after cardiac surgery. Eur J Cardiothorac Surg 1999;16:513-8
  12. Toyoda K. Cerebral Small Vessel Disease and Chronic Kidney Disease. J Stroke 2015;17:31-7
  13. Raskin NH. Neurologicalcomplications of renalfailure. In: Amino MJ, ed. Neurology and general medicine, 2nd ed. New York: Churchill Livingstone 1995;311-3
  14. Ikram MA, Vernooij MW, Hofman A, Niessen WJ, van der Lugt A, Breteler MM. Kidney f