Dergiler / Ulusal Travma ve Acil Cerrahi Dergisi / 2021 / Cilt: 27 - Sayı: 2

External validation of the AppendistatTM score and comparison with CRP levels for the prediction of complicated appendicitis

Sayfa
187–191
Yayın Tarihi
2022-11-06
DOI
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However, C-reactive protein detecting or excluding complicated appendicitis at a similar rate to AppendistatTM suggests that the latter does not have a significant advantage in clinical practice.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:BACKGROUND: In acute appendicitis, the treatment approach may vary depending on the age and comorbidities of the patient and whether the appendix is complicated.
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Temel Bulgular & Veri:METHODS: Demographic characteristics, pathology, and laboratory results of patients who underwent appendectomy for acute appendicitis were retrospectively screened, those over 18 years of age were included in the study.
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Sonuç & Katkı:However, C-reactive protein detecting or excluding complicated appendicitis at a similar rate to AppendistatTM suggests that the latter does not have a significant advantage in clinical practice.
🔬Tür:Modelleme & Sayısal Simülasyon
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

BACKGROUND: In acute appendicitis, the treatment approach may vary depending on the age and comorbidities of the patient and whether the appendix is complicated. In this study, we validated the appendistatTM score, including the logistic regression model of complicated appendicitis, and compared the efficacy of this scoring with C-reactive protein in predicting complicated appendicitis. METHODS: Demographic characteristics, pathology, and laboratory results of patients who underwent appendectomy for acute appendicitis were retrospectively screened, those over 18 years of age were included in the study. The appendistatTM scores, including the logistic regression model of complicated appendicitis, were obtained. RESULTS: Complicated appendicitis was present in 13 (10.1%) patients and non-complicated appendicitis in 116 (89.9%). Two (15.4%) of the complicated appendicitis cases were female and 11 (84.6%) were male. The mean age of complicated appendicitis cases was 44 (20–77) years, and their median value of C-reactive protein was 41.00 mg/L. In the ROC curve analysis, the cut-off value for C-reactive protein was 23.5 mg/L and that of the appendistatTM as 9.6. The area under the curve values of the appendistatTM score and C-reactive protein were 0.787 and 0.750, respectively. CONCLUSION: AppendistatTM is a successful scoring system that contains appropriate parameters. However, C-reactive protein detecting or excluding complicated appendicitis at a similar rate to AppendistatTM suggests that the latter does not have a significant advantage in clinical practice.

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Bu Makaleye Atıf Yap

Tez, M., M.D, M., Sönmez, B. M., M.D, M., Kösa, M. T., M.D., M., Özden, S., M.D, M., Er, S., M.D, M., Birben, B., M.D, M. (2022). External validation of the AppendistatTM score and comparison with CRP levels for the prediction of complicated appendicitis. Ulusal Travma ve Acil Cerrahi Dergisi, Cilt: 27 - Sayı: 2, 187–191. https://ajindex.com/articles/644114

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Kaynakça (13)

  1. Papandria D, Goldstein SD, Rhee D, Salazar JH, Arlikar J, Gorgy A, et al. Risk of perforation increases with delay in recognition and surgery for acute appendicitis. J Surg Res 2013;184:723−9
  2. Eddama M, Fragkos KC, Renshaw S, Aldridge M, Bough G, Bonthala L, et al. Logistic regression model to predict acute uncomplicated and complicated appendicitis. Ann R Coll Surg Engl.2019;101:107−18
  3. Dhillon NK, Barmparas G, Lin TL, Alban RF, Melo N, Yang AR, et al. Unexpected complicated appendicitis in the elderly diagnosed with acute appendicitis. Am J Surg 2019;218:1219−22
  4. Dal F, Cicek Y, Pekmezci S, Kocazeybek B, Tokman HB, Konukoglu D, et al. Role of Alvarado score and biological indicators of C-reactive protein, procalicitonin and neopterin in diagnosis of acute appendicitis. Ulus Travma Acil Cerrahi Derg 2019;25:229−37
  5. Emmanuel A, Murchan P, Wilson I, Balfe P. The value of hyperbilirubinaemia in the diagnosis of acute appendicitis. Ann R Coll Surg Engl 2011;93:213−7
  6. Abbo O, Trabanino C, Pinnagoda K, Ait Kaci A, Carfagna L, Mouttalib S, et al. Non-operative Management for Uncomplicated Appendicitis: An Option to Consider. Eur J Pediatr Surg 2018;28:18−21
  7. Charalampopoulos A, Dimopoulos I, Koliakos N, Kopanakis K, And TL; -. Non-Complicated Acute Appendicitis in Adults Treated Successfully by Conservative Treatment without Recurrences. Chirurgia (Bucur) 2017;112:25−32
  8. Kim M, Kim SJ, Cho HJ. International normalized ratio and serum C-reactive protein are feasible markers to predict complicated appendicitis. World J Emerg Surg 2016;11:31
  9. Kim TH, Cho BS, Jung JH, Lee MS, Jang JH, Kim CN. Predictive Factors to Distinguish Between Patients With Noncomplicated Appendicitis and Those With Complicated Appendicitis. Ann Coloproctol 2015;31:192−7
  10. Lin Y, Wang S, Yang Z, Gao L, Zhou Z, Yu P, et al. Bilirubin alleviates alum-induced peritonitis through inactivation of NLRP3 inflammasome. Biomed Pharmacother 2019;116:108973
  11. Eren T, Tombalak E, Ozemir IA, Leblebici M, Ziyade S, Ekinci O, et al. Hyperbilirubinemia as a predictive factor in acute appendicitis. Eur J Trauma Emerg Surg 2016;42:471−6
  12. Sandstrom A, Grieve DA. Hyperbilirubinaemia: its utility in non-perforated appendicitis. ANZ J Surg 2017;87:587−90
  13. Chambers AC, Bismohun SL, Davies H, White P, Patil AV. Predictive value of abnormally raised serum bilirubin in acute appendicitis: a cohort study. Int J Surg 2015;13:207−10.