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Dergiler / Türk Onkoloji Dergisi / 2020 / Cilt: 35 - Sayı: 4

Ovarian Metastasis of ALK Translocation-Positive LungAdenocarcinoma: A Case Report

Devrim ÇABUK
Şener GEZER
İzzet YÜCESOY
Lale AKSOY
Seda Duman ÖZTÜRK
Sevgiye Kaçar ÖZKARA
Sayfa
475–478
Yayın Tarihi
2022-11-06
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The possibility of ovarian metastasis in female N-SCLC patients with ALK rearrangement should be kept in mind.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Ovarian metastasis is substantially rare in non-small cell lung cancer (N-SCLC).
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Temel Bulgular & Veri:Driver gene mutations, such as Anaplastic Lymphoma Kinase (ALK), are used in the diagnosis of N-SCLC and its metastases.
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Sonuç & Katkı:The possibility of ovarian metastasis in female N-SCLC patients with ALK rearrangement should be kept in mind.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Ovarian metastasis is substantially rare in non-small cell lung cancer (N-SCLC). Driver gene mutations, such as Anaplastic Lymphoma Kinase (ALK), are used in the diagnosis of N-SCLC and its metastases. Demonstration of ALK mutation in N-SCLC patients will be helpful for detecting ovarian metastasis and planning personalized therapy; however, there is a limited number of cases related to this topic. In this case, we present the diagnosis and treatment of ALK-positive non-small cell lung adenocarcinoma patient with ovarian metastasis. Crizotinib is the first-class tyrosine kinase inhibitor using for the treatment of ALK-positive N-SCLC. The ovarian metastasis has been treated with surgery while under Crizotinib treatment. The patient continues to receive crizotinib treatment and no new metastases were detected at the end of a one-year follow-up. The possibility of ovarian metastasis in female N-SCLC patients with ALK rearrangement should be kept in mind.

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Bu Makaleye Atıf Yap

ÇABUK, D., GEZER, Ş., YÜCESOY, İ., AKSOY, L., ÖZTÜRK, S. D., ÖZKARA, S. K. (2022). Ovarian Metastasis of ALK Translocation-Positive LungAdenocarcinoma: A Case Report. Türk Onkoloji Dergisi, Cilt: 35 - Sayı: 4, 475–478. https://ajindex.com/articles/639198

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Kaynakça (9)

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