Dergiler / Türk Onkoloji Dergisi / 2021 / Cilt: 36 - Sayı: 3

The Importance of Apoptosis in Cancer Development and Treatment

Sayfa
381–388
Yayın Tarihi
2022-11-06
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

A better understanding of the molecular events that regulate apoptosis in cancers and cancer therapy form the basis of a more rational approach to the development of molecular targeted therapies in the fight against cancer.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Cancer is one of the most important causes of death in our era.
📊
Temel Bulgular & Veri:Multifactorial causes are involved in the formation of cancer.
💡
Sonuç & Katkı:A better understanding of the molecular events that regulate apoptosis in cancers and cancer therapy form the basis of a more rational approach to the development of molecular targeted therapies in the fight against cancer.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Cancer is one of the most important causes of death in our era. Multifactorial causes are involved in the formation of cancer. The reduction of apoptosis is one of these reasons. Failure to activate apoptosis pathways can lead to resistance to the current treatment approaches of cancers. A better understanding of the molecular events that regulate apoptosis in cancers and cancer therapy form the basis of a more rational approach to the development of molecular targeted therapies in the fight against cancer.

🔖

Bu Makaleye Atıf Yap

KASAP, E., ATAY, İ. N. G., GEZER, A. H. (2022). The Importance of Apoptosis in Cancer Development and Treatment. Türk Onkoloji Dergisi, Cilt: 36 - Sayı: 3, 381–388. https://ajindex.com/articles/639092

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (19)

  1. Cohen JJ. Apoptosis to be or not to be. Vol
  2. Postgraduate Syllabus (AA-AA-I); 1998. p. 1–19
  3. Sanmartín C, Plano D, Palop JA. Selenium compounds and apoptotic modulation: A new perspective in cancer therapy. Mini Rev Med Chem 2008;8(10):1020–31
  4. Baykara O. Current Modalities in Treatment of Cancer. Balikesir Saglik Bil Derg Cilt: 5 Sayı: 3; 2016
  5. Fadeel B, Orrenius S, Zhivotovsky B. Apoptosis in human disease: A new skin for the old ceremony? Biochem Biophys Res Commun 1999;266(3):699–717
  6. Cummings MC, Winterfold CM, Walker NI. Apoptosis. Am J Surg Pathal 1997;21(1):88–101
  7. Koff JL, Ramachandiran S, Bernal-Mizachi L. A time to kill: Targeting apoptosis in cancer. Int J Mol Sci 2015;16(2):2942–55
  8. Sprick MR, Walczak H. The interplay between the Bcl-2 family and death receptor-mediated apoptosis. Biochim Biophys Acta 2004;1644(2–3):125–32
  9. Falschlehner C, Emmerich CH, Gerlach B, Walczak H. TRAIL signalling: Decisions between life and death. Int J Biochem Cell Biol 2007;39(7–8):1462–75
  10. Barnhart BC, Alappat EC, Peter ME. The CD95 Type I/Type II model. Semin Immunol 2003;15(3):185–93
  11. Nitulescu GM, Draghici C, Olaru OT, Matei L, Loana A, Dragu LD, et al. Synthesis and apoptotic activity of new pyrazole derivatives in cancer cell lines. Bioorg Med Chem 2015;23(17):5799–808
  12. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100(1):57–70
  13. Soini Y, Paakkö P, Lehto VP. Histopathological evaluation of apoptosis in cancer. Am J Pathol 1998;153(4):1043–9
  14. BenJilani KE, Gaillard JP, Petit F, Arnoult D, Roumier AS, Labalette M, et al. A suppressive effect of the adenovirus 5 protein E1B 55K on apoptosis induced by IL-3 deprivation and gamma-irradiation. Biol Cell 2002;94(2):77–89
  15. Mehmet H, Laurenzi VD, Stassi G, Walczak H. Programmed cell death in disease. In: Teaching Workshop on Apoptosis. 1st ed. İzmir: Dokuz Eylül University Institute of Health Sciences; 2006. p. 12–7
  16. Miyashita T, Krajewski S, Krajewska M, Wang HG, Lin HK, Liebermann DA, et al. Tumor suppressor p53 is a regulator of bcl-2 and baxgene expression in vitro and in vivo. Oncogene 1994;9(6):1799–805
  17. Vaux DL. Immunopathology of apoptosis introduction and overview. Springer Semin Immunopathol 1998;19(3):271–8
  18. Call JA, Eckhardt SG, Camidge DR. Targeted manipulation of apoptosis in cancer treatment. Lancet Oncol 2008;9(10):1002–11
  19. Sheng S, Zheng J, Cui S, Cui X, Qian Z. Complete remission of multiple lung metastases after ablation