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Dergiler / Türk Oftalmoloji Dergisi / 2017 / Cilt: 47 - Sayı: 2

The Relationship between Serum Carbonic Anhydrase I-II Autoantibody Levels and Diabetic Retinopathy in Type 1 Diabetes Patients

Ahmet ALVER
Ahmet MENTEŞE
İrfan NUHOĞLU
Süleyman MOLLAMEHMETOĞLU
Halil İbrahim İMAMOĞLU
Cihangir EREM
Adem TÜRK
Sayfa
85–88
Yayın Tarihi
2022-11-05
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

However, there was no correlation between the autoantibody levels and the presence of diabetic macular edema in caseswith DRP.

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Amaç & Hipotez:Objectives: To investigate the relationship between serum carbonic anhydrase I-II (CA-I and II) autoantibody levels and diabeticretinopathy (DRP) in cases with type 1 diabetes.Materials and Methods: A total of 37 type-1 diabetic patients, 17 with DRP (group 1) and 20 without (group 2), and 38 healthycontrol subjects (group 3) were included.
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Temel Bulgular & Veri:Additionally, the correlation between CA-I and CA-II autoantibody levels and the presenceof diabetic macular edema was examined.Results: Mean measured CA-I autoantibody levels were 0.145±0.072, 0.117±0.047, and 0.138±0.061 ABSU in group 1, group 2, andgroup 3, respectively (p=0.327).
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Sonuç & Katkı:However, there was no correlation between the autoantibody levels and the presence of diabetic macular edema in caseswith DRP.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Objectives: To investigate the relationship between serum carbonic anhydrase I-II (CA-I and II) autoantibody levels and diabeticretinopathy (DRP) in cases with type 1 diabetes.Materials and Methods: A total of 37 type-1 diabetic patients, 17 with DRP (group 1) and 20 without (group 2), and 38 healthycontrol subjects (group 3) were included. CA-I and CA-II autoantibody levels were measured in serum samples obtained from each ofthe three groups and compared statistically. Additionally, the correlation between CA-I and CA-II autoantibody levels and the presenceof diabetic macular edema was examined.Results: Mean measured CA-I autoantibody levels were 0.145±0.072, 0.117±0.047, and 0.138±0.061 ABSU in group 1, group 2, andgroup 3, respectively (p=0.327). The average CA-II autoantibody levels achieved in the same groups were 0.253±0.174, 0.155±0.137,and 0.131±0.085 ABSU, respectively (p=0.005). No significant difference was obtained between the subgroups of group 1, with macularedema (n=8) and without (n=9), in terms of both CA-I and CA-II autoantibody levels (p=0.501, p=0.178, respectively).Conclusion: A significant correlation was observed between the development of DRP and serum CA-II autoantibody levels in type 1diabetic cases. However, there was no correlation between the autoantibody levels and the presence of diabetic macular edema in caseswith DRP.

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Bu Makaleye Atıf Yap

ALVER, A., MENTEŞE, A., NUHOĞLU, İ., MOLLAMEHMETOĞLU, S., İMAMOĞLU, H. İ., EREM, C., TÜRK, A. (2022). The Relationship between Serum Carbonic Anhydrase I-II Autoantibody Levels and Diabetic Retinopathy in Type 1 Diabetes Patients. Türk Oftalmoloji Dergisi, Cilt: 47 - Sayı: 2, 85–88. https://ajindex.com/articles/637822

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Kaynakça (11)

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