Viability, apoptosis,proliferation, and senescence of the cells were evaluated in control and drug-treated cultures at the end of 72 hours.Results: Cells treated with aflibercept showed increased viability and decreased apoptosis compared to the control culture and boththe bevacizumab- and ranibizumab-treated groups (p
📌 3 Maddede Bu Makale
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Amaç & Hipotez:Objectives: To assess the effects of anti-vascular endothelial growth factor (VEGF) drugs on retinal pigment epithelium cell culture.Materials and Methods: Aflibercept (0.5 mg/mL), bevacizumab (0.3125 mg/mL), and ranibizumab (0.125 mg/mL) were appliedto retinal pigment epithelium cell cultures isolated from the enucleated eyes of New Zealand white rabbits.
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Temel Bulgular & Veri:Objectives: To assess the effects of anti-vascular endothelial growth factor (VEGF) drugs on retinal pigment epithelium cell culture.Materials and Methods: Aflibercept (0.5 mg/mL), bevacizumab (0.3125 mg/mL), and ranibizumab (0.125 mg/mL) were appliedto retinal pigment epithelium cell cultures isolated from the enucleated eyes of New Zealand white rabbits.
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Sonuç & Katkı:Viability, apoptosis,proliferation, and senescence of the cells were evaluated in control and drug-treated cultures at the end of 72 hours.Results: Cells treated with aflibercept showed increased viability and decreased apoptosis compared to the control culture and boththe bevacizumab- and ranibizumab-treated groups (p
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri
Abstract
Objectives: To assess the effects of anti-vascular endothelial growth factor (VEGF) drugs on retinal pigment epithelium cell culture.Materials and Methods: Aflibercept (0.5 mg/mL), bevacizumab (0.3125 mg/mL), and ranibizumab (0.125 mg/mL) were appliedto retinal pigment epithelium cell cultures isolated from the enucleated eyes of New Zealand white rabbits. Viability, apoptosis,proliferation, and senescence of the cells were evaluated in control and drug-treated cultures at the end of 72 hours.Results: Cells treated with aflibercept showed increased viability and decreased apoptosis compared to the control culture and boththe bevacizumab- and ranibizumab-treated groups (p
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Bu Makaleye Atıf Yap
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