Allerjik bronkopulmoner aspergilloz: 3 olgu nedeniyle

Allerjik bronkopulmoner aspergilloz (ABPA) astım olgularının %1-7.6’sında görülmektedir. Bu insidans değeri tanıda akla gelmeyecek kadar düşük ancak önemli bir hastalık olabilecek kadar yüksek bir değerdir. ABPA için spesifik semptom ve laboratuvar testlerinin olmaması olguların yıllarca tanı alamamasına neden olabilir. Ancak tanı ve tedavi gecikmesi fibrotik akciğer hastalığı ile sonuçlanabilmektedir. Bu yazıda ABPA’nın kliniği, laboratuvar verileri ve tedavisi üç olgu üzerinden tartışılacaktır.

Abstract

Allergic bronchopulmonary aspergillosis (ABPA) occurs in approximately 1-7.6% of patients with asthma. This incidence is low enough not to be considered in the differential diagnosis but also high enough to be an important disease. Since the symptoms and laboratory tests are not specific for ABPA, the diagnosis may be delay for years. However the failure to diagnose and treat ABPA for long term may result in fibrotic lung disease. This article focuses on the clinical and the laboratory aspects, and the management of ABPA in the light of three cases.

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Bu Makaleye Atıf Yap

GÖKSEL, Ö., BAVBEK, S., DEMİREL, Y., AYDIN, Ö., MUNGAN, D., MISIRLIGİL, Z., ERKEKOL, Ö. F., CAN, B. A. (2022). Allerjik bronkopulmoner aspergilloz: 3 olgu nedeniyle. Tüberküloz ve Toraks, Cilt: 55 - Sayı: 4, 418–428. https://ajindex.com/articles/619062

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Kaynakça (15)

Shah A. Allergic bronchopulmonary aspergillosis. Allergy Clin Immunol Int-J World Allergy Org 2005; 17:172-80
Greenberger PA. Allergic bronchopulmonary aspergillosis. In: E Middleton (Jr), CE Reed, EF Ellis, AN Franklin (Jr), JW Yunginger, WW Busse (eds). Allergy: Principles and Practice. 5th ed. St Louis: Mosby, 1998: 981-93
Maurya V, Gugnani SC, Sarma PU, et al. Sensitization to Aspergillus antigens and occurrence of allergic bronchopulmonary aspergillosis in patients with asthma. Chest 2005; 127: 1252-9
Schwartz HJ, Greenberger PA. The prevalence of allergic bronchopulmonary aspergillosis in patients with asthma, determined by serologic and radiologic criteria in patients at risk. J Lab Clin Med 1991; 117: 138-42
Patterson R, Greenberger PA. Potential errors in the diagnosis and management of allergic bronchopulmonary aspergillosis. In: Patterson R, Greenberger PA, Roberts ML (eds). Allergic Bronchopulmonary Aspergillosis. 1st ed. Rhode Island: OceanSide, 1995: 29-33
Patterson R, Greenberger PA, Roberts M. The diagnosois of allergic bronchopulmonary aspergillosis. In: Patterson R, Greenberger PA, Roberts ML (eds). Allergic Bronchopulmonary Aspergillosis. 1st ed. Rhode Island: OceanSide, 1995: 1-3
Tillie-Leblond I, Tonnel AB. Allergic bronchopulmonary aspergillosis. Allergy 2005; 60: 1004-13
Greenberger PA, Miller TP, Roberts M, Smith LL. Allergic bronchopulmonary aspergillosis in patients with and without evidence of bronchiectasis. Ann Allergy 1993; 70: 333-8
Berkin KE, Vernon DR, Kerr JW. Lung collapse caused by allergic bronchopulmonary aspergillosis in nonasthmatic patients. Br Med J 1982; 285: 552-3
Glancy JJ, Elder JL, Mcaleer R. Allergic bronchopulmonary fungal disease without clinical asthma. Thorax 1981; 36: 345-9
Shah A, Maurya V, Panjabi C, Khanna P. Allergic bronchopulmonary aspergillosis without clinical asthma caused by Aspergillus niger. Allergy 2004; 59: 236-7
Sider L. Radiology of ABPA. In: Patterson R, Greenberger PA, Roberts ML (eds). Allergic Bronchopulmonary Aspergillosis. 1st ed. Rhode Island: OceanSide, 1995: 17-24
Panchal N, Bhagat R, Pant C, Shah A. Allergic bronchopulmonary aspergillosis: The spectrum of computed tomography appearances. Respir Med 1997; 91: 213-9
Murphy D, Lane DJ. Pleural effusion in allergic bronchopulmonary aspergillosis: Two case reports. Br J Dis Chest 1981; 75: 91-5
Shah A, Aggarwal AK, Chugh IM. Hilar adenopathy in allergic bronchopulmonary