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Dergiler / Turkish Journal of Veterinary and Animal Sciences / 2014 / Cilt: 38 - Sayı: 5

Phylogenetic analysis of NS gene of avian infuenza viruses (H9N2) isolated from chicken in Iran during 2007 2011

Hassan NOROUZIAN
Hessam CHASHM EMADI
Ziba NAZARI
Mehdi MARAND VASFI
Sayfa
501–513
Yayın Tarihi
2022-11-05
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Te potential risk of the emergence of apandemic virus because of the reassortment of the internal genes between H9N2 viruses and highly pathogenic AI viruses on one handand the genetic and amino acid changes of AI viruses afecting their pathogenicity and immunogenicity on the other hand confrm theimportance of continued surveillance of AI viruses.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:To determine sequence characteristics and phylogenetic relationships of the nonstructural (NS) gene, the NS genes of 9 avianinfuenza (AI) viruses were sequenced and compared with other Iranian AI H9N2 viruses available in GenBank.
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Temel Bulgular & Veri:Te similarity amongthe earliest Iranian H9N2 isolate (A/chicken/Iran/ZMT-101/1998) and recent (2007 2011) studied isolates was low (94%).
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Sonuç & Katkı:Te potential risk of the emergence of apandemic virus because of the reassortment of the internal genes between H9N2 viruses and highly pathogenic AI viruses on one handand the genetic and amino acid changes of AI viruses afecting their pathogenicity and immunogenicity on the other hand confrm theimportance of continued surveillance of AI viruses.
🔬Tür:Araştırma Makalesi
📍Kapsam:2007 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

To determine sequence characteristics and phylogenetic relationships of the nonstructural (NS) gene, the NS genes of 9 avianinfuenza (AI) viruses were sequenced and compared with other Iranian AI H9N2 viruses available in GenBank. Te similarity amongthe earliest Iranian H9N2 isolate (A/chicken/Iran/ZMT-101/1998) and recent (2007 2011) studied isolates was low (94%). Some of thestudied viruses revealed substitutions in RNA-binding and efector domains as well as antigenic regions of the NS protein. Recentlystudied isolates have a high similarity (97.4% 98.7%) with some Pakistani isolates (like A/chicken/Sawabi/NARC-2434/2006) in the NSgene. In the phylogenetic analysis, recently studied isolates composed a cluster separate from other Iranian isolates and were placed inthe neighborhood of some Pakistani isolates. Hence, new Iranian H9N2 isolates may originate from Pakistani isolates. Te NS proteinof the Iranian H9N2 isolates difered from that of the Iranian highly pathogenic H5N1 viruses. Te potential risk of the emergence of apandemic virus because of the reassortment of the internal genes between H9N2 viruses and highly pathogenic AI viruses on one handand the genetic and amino acid changes of AI viruses afecting their pathogenicity and immunogenicity on the other hand confrm theimportance of continued surveillance of AI viruses.

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Bu Makaleye Atıf Yap

NOROUZIAN, H., EMADI, H. C., NAZARI, Z., VASFI, M. M. (2022). Phylogenetic analysis of NS gene of avian infuenza viruses (H9N2) isolated from chicken in Iran during 2007 2011. Turkish Journal of Veterinary and Animal Sciences, Cilt: 38 - Sayı: 5, 501–513. https://ajindex.com/articles/615246

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Kaynakça (16)

  1. Alexander DJ. An overview of the epidemiology of avian infuenza. Vaccine 2007; 25: 5637–5644
  2. Yasuda J, Nakada S, Kato A, Toyoda T, Ishihama A. Molecular assembly of infuenza: association of the NS2 protein with virion matrix. Virology 1993; 196: 249–255
  3. Nili H, Asasi K. Avian infuenza (H9N2) outbreak in Iran. Avian Dis 2003; 47: 828–831
  4. Bano S, Naeem K, Malik SA. Evaluation of pathogenic potential of avian infuenza virus serotype H9N2 in chickens. Avian Dis 2003; 47: 817–822
  5. Lamb RA, Chopin PW, Chanock RM, Lai CJ. Mapping of the two overlapping genes for polypeptides NS1 and NS2 on RNA segment 8 of infuenza virus genome. P Natl Acad Sci USA 1980; 77: 1857–1861
  6. Suarez DL, Perdue ML. Multiple alignment comparison of the non-structural genes of infuenza A viruses. Virus Res 1998; 54: 59–69
  7. Lazarowitz SG, Compans RW, Choppin PW. Infuenza virus structural and nonstructural proteins in infected cells and their plasma membranes. Virology 1971; 46: 830–843
  8. Tumpey TM, Alvarez R, Swayne DE, Suarez DL. Molecular assembly of infuenza virus: association of the NS2 protein with virion matrix. J Clin Microbiol 2005; 43: 676–683
  9. Panshin A, Golender N, Davidson I, Nagar S, Garsia M, Jackwood MW, Mundt E, Alturi A, Perk S. Variability of NS1 proteins among H9N2 avian infuenza viruses isolated in Israel during 2000–2006. Virus Gen 2010; 41: 396–405
  10. Lin D, Lan J, Zhang Z. Structure and function of the NS1 protein of infuenza A virus. Acta Bioch Bioph Sinica 2007; 39: 155–162
  11. Yin C, Khan JA, Swapna GVT, Ertekin A, Krug RM, Tong L, Montelione GT. Conserved surface features from the double- stranded RNA binding site of non-structural protein 1 (NS1) from infuenza A and B viruses. J Biol Chem 2007; 282: 20584– 20595
  12. Hale BG, Randall RE, Ortin J, Jackson D. Te multifunctional NS1 protein of infuenza A viruses. J Gen Virol 2008; 89: 2359– 2376
  13. Banet-Noach C, Panshin A, Golender N, Simanov L, Rozanblut E, Pokamunski S, Pirak M, Tendler Y, Garcia M, Gelman B et al. Genetic analysis of nonstructural genes (NS1 and NS2) of H9N2 and H5N1 viruses recently isolated in Israel. Virus Genes 2007; 34: 157–168
  14. Seo SH, Hofmann E, Webster RG. Lethal H5N1 infuenza viruses escape host anti-viral cytokine responses. Nat Med 2002; 8: 950–954
  15. O’Neill RE, Talon J, Palese P. Te infuenza virus NEP (NS2 protein) mediates the nuclear export of viral ribonucleoproteins. EMBO J 1998; 17: 288–296
  16. Iqbal M, Yaqub T, Reddy K, McCauley JW. Nov