KaydedilenlerDerginizi ekleyin

Dergiler / Turkish Journal of Veterinary and Animal Sciences / 2017 / Cilt: 41 - Sayı: 2

An investigation of antibacterial effects of steroids

Neslihan MUTLU
Pınar AKSU KILIÇLE
Abdullah DOĞAN
Ali Nazmi Can DOĞAN
Özgür ÇELEBİ
Aliye GÜLMEZ SAĞLAM
Salih OTLU
Sayfa
302–305
Yayın Tarihi
2022-11-05
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

These steroids did not appear to have widespreadantibacterial properties.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:In this study, the effects of steroid substances such as corticosterone, progesterone, estrone, beta-sitosterol, and stigmasterolon some bacteria were investigated.
📊
Temel Bulgular & Veri:In the research, standard strains of the gram-positive bacteriaBacillus subtilis(lab isolate) andStaphylococcus aureus(ATCC 6538) and the gram-negative bacteriaEscherichia coli(ATCC 25922),Pasteurella multocida(ATCC 12945),andPseudomonas aeruginosa(ATCC 9027) were used.
💡
Sonuç & Katkı:These steroids did not appear to have widespreadantibacterial properties.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

In this study, the effects of steroid substances such as corticosterone, progesterone, estrone, beta-sitosterol, and stigmasterolon some bacteria were investigated. In the research, standard strains of the gram-positive bacteriaBacillus subtilis(lab isolate) andStaphylococcus aureus(ATCC 6538) and the gram-negative bacteriaEscherichia coli(ATCC 25922),Pasteurella multocida(ATCC 12945),andPseudomonas aeruginosa(ATCC 9027) were used. A modified broth dilution method was applied for determining the minimalinhibitory concentration (MIC) of the steroids. Mueller Hinton broth (Becton Dickinson, 211443) was used to prepare dilutions andas a medium. At the end of the study, the MIC of corticosterone forP. multocidaand the MIC of beta-sitosterol forS. aureuswere bothdetermined as 32 μg/mL. However, other steroids showed no effects on the bacteria. These steroids did not appear to have widespreadantibacterial properties.

🔖

Bu Makaleye Atıf Yap

MUTLU, N., KILIÇLE, P. A., DOĞAN, A., DOĞAN, A. N. C., ÇELEBİ, Ö., SAĞLAM, A. G., OTLU, S. (2022). An investigation of antibacterial effects of steroids. Turkish Journal of Veterinary and Animal Sciences, Cilt: 41 - Sayı: 2, 302–305. https://ajindex.com/articles/615245

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (14)

  1. Doğan A. Farmakoloji Cilt 1, 2. Ders Notları. Kars, Turkey: Kafkas Üniversitesi Veteriner Fakültesi; 2014 (in Turkish)
  2. Battaa AK, Xua G, Honda A, Miyazaki T, Salen G. Stigmasterol reduces plasma cholesterol levels and inhibits hepatic synthesis and intestinal absorption in the rat. Metabolism 2006; 55: 292- 299
  3. Garden Guides. List of Plant Sterols. © 2010. Available online at
  4. Doğan A, Otlu S, Büyük F, Aksu P, Tazegül E, Erdağ D. Sisteamin, putresin ve sisteamin-putresin kombinasyonunun bazı bakteriler üzerine etkileri. Kafkas Üniv Vet Fak Derg 2012; 18: 1015-1019 (in Turkish)
  5. Vida N, Svobodova H, Rarova L, Drašar P, Saman D, Cvacka J, Wimmera Z. Polyamine conjugates of stigmasterol. S teroids 2012; 77: 1212-1218
  6. Doğaneli, MZ, Aydın N, Alaçam E. Koyunlarda östrus siklusunun değişik dönemlerinde uterusun infeksiyonlara karşı koyma gücü üzerine araştırma. AÜ Vet Fak Derg 1978; 25: 674-685 (in Turkish)
  7. Wiegand I, Hilpert K, Hancock REW. Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances. Nat Protoc 2008; 3: 163- 175
  8. Ericsson HM, Sherris JC. Antibiotic sensitivity testing: report of an international collaborative study. Acta Path Micro Im B 1971; 217: 1-90
  9. Stepanovic S, Djukic S, Veljkovic M, Arsic B, Garalejic E, Ranin L. Antimicrobial activity of human follicular fluids. Gynecol Obstet Inves 2003; 56: 173-178
  10. Gurgan T, Urman B, Diker KS, Delilbasi L, Kisnisci HA. Human follicular-fluid from preovulatory follicles in patients undergoing in vitro fertilization inhibits the in vitro growth of gram-positive microorganisms. Hum Reprod 1993; 8: 508-510
  11. Johnson JU, Oxender WD, Berkhoff HA. Influence of estrogen on antibacterial and immunoglobulin secretory activities of uterine fluids from ovariectomized mares. Am J Vet Res 1994; 55: 643-649
  12. Polat ZA, Savage PB, Genberg C. In vitro amoebicidal activity of a ceragenin, cationic steroid antibiotic-13, against Acanthamoeba castellanii and its cytotoxic potential. J Ocul Pharmacol Th 2011; 27: 1-5
  13. Bucki R, Leszczynska K, Byfield FJ, Fein DE, Won E, Cruz K, Namiot A, Kulakowska A, Namiot Z, Savage PB et al. Combined antibacterial and anti-inflammatory activity of a cationic disubstituted dexamethasone–spermine conjugate. Antimicrob Agents Ch 2010; 54: 2525-2533
  14. Figueroa-Valverde L, Diaz-Cedillo F, Camacho-Luis A, Lopez- Ramos M. Synthes