Yapay Zeka Hızlı Bakış & Çıkarımlar
AI InsightWith the exception of the heart SOD activity, the additional intake of vitamin E reduced antioxidantenzyme activity and augmented the GSH level, indicating an enhancement in the nonenzymatic part of the antioxidant network.
📌 3 Maddede Bu Makale
Abstract
The α-tocopherol (TCP) state as well as enzymatic (superoxide dismutase [SOD] and catalase [CAT]) and nonenzymatic(reduced glutathione [GSH] and retinol) antioxidants in tissues of American minks (Neovison vison) given various levels of dietaryvitamin E were examined. Three groups of farm-bred minks received different amounts of DL-α-tocopheryl acetate (10 mg/kg diet,control; 30 and 110 mg/kg diet, treatments denoted as E30 and E110, respectively) for 14 days in November. The TCP content was raisedsubstantially in the kidneys and reduced in the livers of minks in the E110 group. The action of the 2 vitamin E doses on antioxidantswas similar. The treatments resulted in lower hepatic and kidney retinol levels and hepatic and skeletal muscle SOD, as well as hepaticCAT activities, higher heart SOD activity, and higher kidney GSH content in comparison to the control group. The present results showthat dietary vitamin E intake over 2 weeks considerably changed the TCP status of the liver and kidneys and had tissue-specific actionon measured antioxidants in minks. With the exception of the heart SOD activity, the additional intake of vitamin E reduced antioxidantenzyme activity and augmented the GSH level, indicating an enhancement in the nonenzymatic part of the antioxidant network.