Comprehensive analysis indicated that the polymorphisms of exon 10 in the BPI gene have significant geneticeffects on some reproductive traits and cytokines in Meishan pigs, for which the AA genotype was demonstrated to be the favorablegenotype, which could be used as potential genetic markers for in-depth research and examination.
📌 3 Maddede Bu Makale
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Amaç & Hipotez:This study was conducted to detect polymorphisms of BPI gene exon 10 by PCR-RFLP in Meishan pigs and their associationswith some important cytokine levels (IL-1β, IL-4, IL-6, IL-8, IL-10, TGF-1β, IFN-γ, TNF-α) and reproductive traits (total number born(TNB), number born alive (NBA), birth litter weight (BLW), and weaning litter weight (WLW)), with the aim of identifying effectivegenetic markers for molecular breeding.
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Temel Bulgular & Veri:Pigs with the AA genotype were significantly higher than the AB genotype in TNB and IFN-γ (P 0.05).
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Sonuç & Katkı:Comprehensive analysis indicated that the polymorphisms of exon 10 in the BPI gene have significant geneticeffects on some reproductive traits and cytokines in Meishan pigs, for which the AA genotype was demonstrated to be the favorablegenotype, which could be used as potential genetic markers for in-depth research and examination.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri
Abstract
This study was conducted to detect polymorphisms of BPI gene exon 10 by PCR-RFLP in Meishan pigs and their associationswith some important cytokine levels (IL-1β, IL-4, IL-6, IL-8, IL-10, TGF-1β, IFN-γ, TNF-α) and reproductive traits (total number born(TNB), number born alive (NBA), birth litter weight (BLW), and weaning litter weight (WLW)), with the aim of identifying effectivegenetic markers for molecular breeding. The results revealed three genotypes, including AA, AB, and BB, with the trend of AA > BB >AB in reproductive traits. Pigs with the AA genotype were significantly higher than the AB genotype in TNB and IFN-γ (P 0.05). Comprehensive analysis indicated that the polymorphisms of exon 10 in the BPI gene have significant geneticeffects on some reproductive traits and cytokines in Meishan pigs, for which the AA genotype was demonstrated to be the favorablegenotype, which could be used as potential genetic markers for in-depth research and examination.
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Bu Makaleye Atıf Yap
YE, L., WEI, Z., QU, H., BAO, W., WU, S. (2022). Polymorphisms of exon 10 in the BPI gene and its association analysis with some reproductive traits and partial immune indexes in Meishan pigs. Turkish Journal of Veterinary and Animal Sciences, Cilt: 43 - Sayı: 1, 127–133. https://ajindex.com/articles/614844
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