Dergiler / Turkish Journal of Veterinary and Animal Sciences / 2022 / Cilt: 46 - Sayı: 1

Effects of vitamin D administration at the beginning of lactation in dairy cows on inflammatory response and liver metabolism

Sayfa
107–114
Yayın Tarihi
2022-11-03
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In conclusion, it can be suggested that vitamin D administration can prevent SCH after the 3rd day and has limited positive effects on postpartum NEFA levels.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:This study aimed to investigate the effect of vitamin D administered 24 h after calving of dairy cows on calcium-phosphorus metabolism, carbohydrate, lipid and liver metabolism, and inflammatory response.
📊
Temel Bulgular & Veri:The EG received 5,000,000 IU vitamin D3 (5 mL) 24 h after parturition intramuscularly, whereas the CG group received 5 mL of 0.9% NaCl.
💡
Sonuç & Katkı:In conclusion, it can be suggested that vitamin D administration can prevent SCH after the 3rd day and has limited positive effects on postpartum NEFA levels.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

This study aimed to investigate the effect of vitamin D administered 24 h after calving of dairy cows on calcium-phosphorus metabolism, carbohydrate, lipid and liver metabolism, and inflammatory response. Twenty multiparous Holstein cows were randomly assigned to the experimental (EG) and control group (CG). The EG received 5,000,000 IU vitamin D3 (5 mL) 24 h after parturition intramuscularly, whereas the CG group received 5 mL of 0.9% NaCl. Blood samples were taken 24 h after parturition before treatments and at the 3rd, 7th, 14th, and 28th days of lactation. Serum NEFA, BHBA, haptoglobin, serum amyloid A (SAA), ceruloplasmin, calcium, phosphorus, parathormone, total protein, triglyceride, AST, and GGT were measured. In addition, total bilirubin, albumin, total cholesterol, and vitamin A concentrations were also measured to calculate liver activity index and the liver functionality index. Subclinical hypocalcemia (SCH) was observed in only one cow in the EG and five in the CG after the 3rd day postpartum. NEFA levels in the EG significantly differed on days 7, 14, and 28 when compared to vitamin D pretreatment values. However, NEFA levels in the CG differed only between day 28 postpartum and the 1st day (p < 0.05). Negative correlation was determined between vitamin D and NEFA (p < 0.01). Conversely, negative correlations were observed between calcium and NEFA, haptoglobin, SAA (p < 0.05). In conclusion, it can be suggested that vitamin D administration can prevent SCH after the 3rd day and has limited positive effects on postpartum NEFA levels.

🔖

Bu Makaleye Atıf Yap

BATMAZ, H., KAYA, F. (2022). Effects of vitamin D administration at the beginning of lactation in dairy cows on inflammatory response and liver metabolism. Turkish Journal of Veterinary and Animal Sciences, Cilt: 46 - Sayı: 1, 107–114. https://ajindex.com/articles/614541

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (14)

  1. Leblanc S. Monitoring metabolic health of dairy cattle in the transition period. The Journal of reproduction and development 2010; 56: 29-35
  2. Murray RD, Horsfield JD, McCormick WD, Williams H, Ward D. Historical and current perspectives on the treatment, control and pathogenesis of milk fever in dairy cattle. Veterinary Record 2008; 163: 561-565
  3. Martinez N, Risco CA, Lima FS, Bisinotto RS, Greco LF et al. Evaluation of peripartal calcium status, energetic profile, and neutrophil function in dairy cows at low or high risk of developing uterine disease. Journal of Dairy Science 2012; 95: 7158-7172
  4. Bertoni G, Trevisi E. Use of the liver activity index and other metabolic variables in the asssesment of metabolic health in dairy herds. Veterinary Clinics North America Food Animal 2013; 29: 413-431
  5. Martinez N, Sinedino LDP, Bisinotto RS, Ribeiro ES, Gomes GC et al. Effect of induced subclinical hypocalcemia on physiological responses and neutrophil function in dairy cows. Journal of Dairy Science 2014; 97: 874-887
  6. Trevisi E, Minuti A. Assessment of the innate immune response in the periparturient cow. Research Veterinary Science 2018; 116: 47-54
  7. Ceciliani F, Giordano A, Spagnolo V. The systemic reaction during inflammation: the acute phase proteins. Protein and Peptide Letters 2002; 9: 211–23
  8. Ceciliani F, Ceron JJ, Eckersall PD, Saurwein H. Acute-phase proteins in ruminants. Journal of Proteomics 2012; 75: 4207- 4231
  9. Ulutas PA, Ulutas B, Kiral F, Asici GSE, Gültekin M. Changes of acute phase protein levels in Saanen goat kids during neonatal period. Small Ruminant Research 2017; 146: 33-36
  10. Horst RL, Goff JP, Reinhardt TA. Role of vitamin D in calcium homeostasis and its use in prevention of bovine periparturient paresis. Acta Veterinaria Scandinavica Supplement 2003; 97: 35-50
  11. Goff JP. Calcium and magnesium disorders. Veterinary Clinics North America Food Animal 2014; 30: 359-381
  12. Krueger LA, Reinhardt TA, Beitz DC, Stuart RL, Stabel JL. Effects of fractionated colostrum replacer and vitamins A, D, and E on haptoglobin and clinical health in neonatal Holstein calves challenged with Mycobacterium avium ssp. Paratuberculosis. Journal of Dairy Science 2016; 99: 2884-2895
  13. Julien WE, Conrad HR, Hibbs JW, Christ WL. Milk fever in dairy cows. VIII. Effect of injected vitamin D3 and calciumand phosphorus intake on incidence. Journal of Dairy Science 1977; 60: 431-436
  14. Veskoukis AS, Kyparos A., Paschalis V., Nikola