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Dergiler / Turkish Journal of Pharmaceutical Sciences / 2014 / Cilt: 11 - Sayı: 1

Centaurea ensiformis P.H. Davis’in Fenolik Bileşiklerinin Antioksidan Aktiviteleri

Antioxidant Activities of Phenolic Compounds of Centaurea ensiformis P.H. Davis

Petek BALLAR
Şüra BAYKAN EREL
Canan KARAALP
Sayfa
19–24
Yayın Tarihi
2022-11-05
DOI
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Our results concluded that the C. ensiformis have a potential source of antioxidants of natural origin

📌 3 Maddede Bu Makale

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Amaç & Hipotez:The aim of the present study was to investigate the antioxidant activities of 11 phenolic compounds previously isolated from an endemic Centaurea ensiformis P.H.
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Temel Bulgular & Veri:Davis (Asteraceae) by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ABTS decolorization assays.
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Sonuç & Katkı:Our results concluded that the C. ensiformis have a potential source of antioxidants of natural origin
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

The aim of the present study was to investigate the antioxidant activities of 11 phenolic compounds previously isolated from an endemic Centaurea ensiformis P.H. Davis (Asteraceae) by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ABTS decolorization assays. These compounds consisting of 2 phenolic glycosides (tacioside and protocatechuic acid), 2 acetophenon glycosides (picein and 4-hydroxyacetophenon 4-O-[6’O-β-D-apiofuranosyl]-β-D-glucopyranoside), 1 coumarin glucoside (scopolin), 4 flavonoid glycosides (vicenin-2, schaftoside, neoschaftoside and chrysoeriol-7-O-rutinoside), 1 phenylpropanoid glycoside (syringin) and 1 neolignan glucoside (dihydrodehydrodiconiferyl alcohol 4-O-β-D-glucopyranoside). Protocatechuic acid and tachioside had the highest activity (DPPH IC50: 6.47 and 22.87 mM; TEAC: 33.2±0.18 and 31.2±0.99, respectively) in both methods. Dihydrodehydrodiconiferyl alcohol 4-O-β-D-glucopyranoside also showed high activity compared to ascorbic acid in DPPH assay (IC50: 27.7 mM). Our results concluded that the C. ensiformis have a potential source of antioxidants of natural origin

Abstract

Bu çalışmanın amacı endemik Centaurea ensiformis P.H. Davis (Asteraceae)'den daha önce izole edilmiş olan 11 bileşiğin 2,2-difenil-1-pikrilhidrazil (DPPH) ve ABTS dekolorizasyon yöntemleri ile antioksidan aktivitelerinin incelenmesidir. Bu bileşikler 2 fenolik glikozit (taçiozit ve protokateşik asit), 2 asetofenon glikozidi (pisein ve 4-hidroksiasetofenon 4-O-[6'-O-?-D-apiofuranosil]-?-D-glukopiranozit), 1 kumarin glikozidi (skopolin), 4 flavonoit glikozidi (visenin-2, şaftozit, neoşaftozit ve krizoeriyol-7-Orutinozit), 1 fenilpropanoit glikozidi (siringin) ve 1 neolignan glukozidinden (dihidrodehidrodikoniferil alkol 4-O-?-D-glukopiranozit) oluşmaktadır. Taçiozit ve protokateşik asit her 2 metotta da en yüksek aktiviteye sahiptir (DPPH IC50: 6.47 ve 22.87 mM; TEAC: 33.2±0.18 ve 31.2±0.99, sırasıyla). Dihidrodehidrodikoniferil alkol 4-O-?-D-glukopiranozit de DPPH yönteminde askorbik asit ile karşılaştırıldığında yüksek aktivite göstermiştir (IC50: 27.7 mM). Sonuçlarımız, C. ensiformis'in doğal kaynaklı bir antioksidan kaynağı olma potansiyelini ortaya koymaktadır

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Bu Makaleye Atıf Yap

BALLAR, P., EREL, Ş. B., KARAALP, C. (2022). Centaurea ensiformis P.H. Davis’in Fenolik Bileşiklerinin Antioksidan Aktiviteleri. Turkish Journal of Pharmaceutical Sciences, Cilt: 11 - Sayı: 1, 19–24. https://ajindex.com/articles/613888

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Kaynakça (14)

  1. Davis PH, Mill RR, Flora of Turkey, Volume 5, Edinburgh, pp 582, Edinburgh University Press, Edinburgh, 1988
  2. Ekim T, Koyuncu M, Vural M, Duman H, Aytaç Z, Adıgüzel N, Red Data Books on Turkish Plants, Barıscan Press, Ankara, 2000
  3. Baykan Erel Ş, Bedir E, Khan IA, Karaalp C, Secondary metabolites from Centaurea ensiformis P.H. Davis, Biochem Syst Ecol 38(5), 1056- 1058, 2010
  4. Karamenderes C, Demirci B, Baser KHC, Composition of essential oils of ten Centaurea L. taxa from Turkey, J Ess Oil Res 20(4), 342- 349, 2008
  5. Ugur A, Duru ME, Ceylan O, Sarac N, Varol O, Kivrak I, Chemical composition, antimicrobial and antioxidant activities of Centaurea ensiformis Hub.-Mor. (Asteraceae), a species endemic to Mugla (Turkey), Nat Prod Res 23(2), 149-67, 2009
  6. Karamenderes C, Konyalioglu S, Khan S, Khan IA, Total phenolic contents, free radical scavenging activities and inhibitory effects on the activation of NF-kB of eight Centaurea L. species, Phytother Res 21(5), 488-491, 2007
  7. Brand-Williams W, Cuvelier ME, Berset C, Use of a free radical method to evaluate antioxidant activity, Lebensm Wiss Technol 28, 25-30, 1995
  8. Zhang Z, Liao L, Moore J, Wu T, Wang Z, Antioxidant phenolic compounds from walnut kernels (Juglans regia L.), Food Chem 113, 16- 165, 2009
  9. Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C, Antioxidant activity applying an improved ABTS radical cation decolorization assay, Free Rad Biol Med 26, 1231- 1237, 1999
  10. Es-Safia NE, Kollmanna A, Khlific S, Ducrota PH, Antioxidative effect of compounds isolated from Globularia alypum L.structure–activity relationship, LWT-Food Sci Tech 40, 1246- 1252, 2007
  11. Vukics V, Kery A, Bonn GK, Guttman A, Major flavonoid components of heartsease (Viola tricolor L.) and their antioxidant activities, Anal Bioanal Chem 390, 1917-1935, 2008
  12. Delazar A, Sabzevari A, Mojarrab M, Nazemiyeh H, Esnaashari S, Nahar L, Razavi SM, Sarker SD, Free-radical-scavenging principles from Phlomis caucasica, J Nat Med 62, 464- 466, 2008
  13. Pala FS, Gürkan H, The role of free radicals in ethiopathogenesis of diseases, Adv Mol Biol 1, 1-9, 2008
  14. Rohman A, Riyanto S, Yuniarti N, Saputra WR, Utami R, Mulatsih W, Antioxidant activity, total phenolic, and total flavonoid of extracts and fractions of red fruit (Pandanus conoideus Lam), Int Food Res J 17, 97-106, 2010.