Dergiler / Turkish Journal of Medical Sciences / 1999 / Cilt: 29 - Sayı: 6

Lipid peroxidation in Behçet's disease in active and remission periods

Sayfa
661–664
Yayın Tarihi
2022-11-05
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

It was found that mean plasma MDA levels were significantly higher both in the active (11.147 ± 2.452 nmol/mL) and remission (8.056 ± 1.916 nmol/mL) periods in patients with BD than in the controls (4.978 ± 1.431 nmol/mL) (p

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Recent few studies revealed that increased levels of oxygen free radicals might play a role in tissue damage.
📊
Temel Bulgular & Veri:There are some studies in the literature proposing that increased levels of oxygen radicals might play a role in tissue damage, as also seen in Behçet's disease (BD).
💡
Sonuç & Katkı:It was found that mean plasma MDA levels were significantly higher both in the active (11.147 ± 2.452 nmol/mL) and remission (8.056 ± 1.916 nmol/mL) periods in patients with BD than in the controls (4.978 ± 1.431 nmol/mL) (p
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Recent few studies revealed that increased levels of oxygen free radicals might play a role in tissue damage. There are some studies in the literature proposing that increased levels of oxygen radicals might play a role in tissue damage, as also seen in Behçet's disease (BD). The aim of the present study was to measure plasma malondialde-hyde (MDA) (as an index of lipid peroxida-tion) levels in 23 patients with BD (13 men, 10 women with a mean age of 34.5 ± .2 years) both in active and in remission periods. Twenty-one healthy volunteers (11 men, 10 women) formed as the control group. It was found that mean plasma MDA levels were significantly higher both in the active (11.147 ± 2.452 nmol/mL) and remission (8.056 ± 1.916 nmol/mL) periods in patients with BD than in the controls (4.978 ± 1.431 nmol/mL) (p

🔖

Bu Makaleye Atıf Yap

ERDEM, T., AKÇAY, F., ALTUNTAŞ, İ., AKDENİZ, N. (2022). Lipid peroxidation in Behçet's disease in active and remission periods. Turkish Journal of Medical Sciences, Cilt: 29 - Sayı: 6, 661–664. https://ajindex.com/articles/612554

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (15)

  1. he International Study Group forBehçet's disease. Evaluation ofdiagnostic (classification) criteria inBehçet's disease towardsinternationally agreed criteria Br JRheumatol 1992
  2. Jorizzo JL, Solomon AR, Cavallo T.Behçet's syndrome. Immunopathologicand histopathologic assessment ofpathergy lesions is useful in diagnosisand follow-up. Arch Pathol Lab Med1985
  3. 109(8): 747-51. 3.Magro CM, Crowson AN. Cutaneousmanifestations of Behçet's disease.Int J Dermatol 1995
  4. 34(3): 159-65. 4.Lie JT. Vascular involvement in Behçet'sdisease: arterial and venous and vesselsof all sizes. J Rheumatol 1992
  5. 19(3):341-3. 5.Jorizzo JL. Behçet’s disease. In:Moschella SL, Hurley HJ, eds.Dermatology, Third ed. Philadelphia:WB Saunders Company, 1992
  6. Niwa Y, Miyake S, Sakane T, Shinku M,Yokoyama M. Auto-oxidative damagein Behçet’s disease-endothelial celldamage following the elevated oxygenradicals generated by stimulatedneutrophil. Clin Exp Immunol 1990
  7. Köse K, Doğan P, Aşçıoğlu M, Erkılıç K,Aşçıoğlu O. Oxidative stress andantioxidant defenses in plasma ofpatients with Behçet's disease.Tohoku J Exp Med 1995
  8. 176(4):239-48. 8.Yamada M, Mimura Y, Watanabe K,Yuasa T, Murai Y. Neutrophil lysosomeenzyme activities in patients withBehçet’s disease. In: Inaba G ed.Behçet’s Disease. Tokyo: Jpn Med ResFound Pub, 1981
  9. Köse K, Doğan P. Lipid peroksidasyonu.Erciyes Med J 1992
  10. Suppl(1): 340-50. 10.Orem A, Efe H, Değer O, Cimşit G,Uydu HA, Vanizor B. Relationshipbetween lipid peroxidation and diseaseactivity with Behçet's disease. JDermatol Sci 1997
  11. 16(1): 11-6. 11.Sotoh K. Serum lipid peroxide incerebrovascular disorders determinedby a new colorimetric method. ClinChim Acta 1978
  12. Fairburn K, Stevens CR, Winyard PG,Kus M, Ward RJ, Cunningham J, ZaidiM, Blake R. Oxidative stress and itscontrol: A pathogenetic role ininflammatory joint disease. Free radicalresearch joint colloquium. London, 15-18 December 1992. 13.Weiss SJ. Tissue destruction byneutrophils. N Engl J Med 1989
  13. Fantone JC, Ward PA.Polymorphonuclear leukocytemediated cell and tissue injury: Oxygenmetabolites and their relationship tohuman disease.Human Pathol 1985
  14. Klebanoff SJ. Phagocytic cells: Productof oxygen metabolism. In: Gallin JI,Goldstein IM, Synderman R, eds.Inflammation: Basic principles andclinical correlates. New York: RavenPress, 1988
  15. 444 16.Freeman B, Crapo JD. Biology ofdisease, free radicals and tissue injury.Lab Inves