Yapay Zeka Hızlı Bakış & Çıkarımlar
AI InsightBecause of their poor susceptibility rates, cotrimoxazole, penicilins and gentamicin shouldn't be administered empirically, especially to catheterized patients with NUTIs
📌 3 Maddede Bu Makale
Özet
In this prospective study, we found that 21.80% (29/133) of nosocomial urinary tract infections (NUTis) were caused by Escherichia coli, 12.78% (17/133) by Pseudomonas aeruginosa and 10.53% (14/133) by Klebsiella pneumoniae whereas 16.54% (22/133) were caused by coagulase negative staphylococci. The highest susceptibility rate was determined with imipenem among gram negatives (21/28 for non-fermentatives and 65/66 for others); and with vancomycin (30/30) and pristinamycin (29/30) among gram positives. On the other hand, the lowest susceptibilities were to amoxicilin (7/66), amoxicilin clavulonat (18/66) and cotrimoxazole (27/66) among gram negatives other than non-fermentatives. All of the non-fermentative gram negative isolates were resistant to gentamicin (30/30). Most of the P. aeruginosa strains (15/17) were isolated from samples of catheterized patients. Because of their poor susceptibility rates, cotrimoxazole, penicilins and gentamicin shouldn't be administered empirically, especially to catheterized patients with NUTIs
Abstract
In this prospective study, we found that 21.80% (29/133) of nosocomial urinary tract infections (NUTis) were caused by Escherichia coli, 12.78% (17/133) by Pseudomonas aeruginosa and 10.53% (14/133) by Klebsiella pneumoniae whereas 16.54% (22/133) were caused by coagulase negative staphylococci. The highest susceptibility rate was determined with imipenem among gram negatives (21/28 for non-fermentatives and 65/66 for others); and with vancomycin (30/30) and pristinamycin (29/30) among gram positives. On the other hand, the lowest susceptibilities were to amoxicilin (7/66), amoxicilin clavulonat (18/66) and cotrimoxazole (27/66) among gram negatives other than non-fermentatives. All of the non-fermentative gram negative isolates were resistant to gentamicin (30/30). Most of the P. aeruginosa strains (15/17) were isolated from samples of catheterized patients. Because of their poor susceptibility rates, cotrimoxazole, penicilins and gentamicin shouldn't be administered empirically, especially to catheterized patients with NUTIs