Dergiler / Turkish Journal of Medical Sciences / 2002 / Cilt: 32 - Sayı: 1

Nosocomial Fungal Infections in a Teaching Hospital in Turkey: Identification of the Pathogens and Their Antifungal Susceptibility Patterns

Sayfa
35–38
Yayın Tarihi
2022-11-05
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The resistance to miconazole, econazole and ketoconazole was higher at 18.8%, 15.8% and 23.6% respectively.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:From January 1999 through April 2000, 208 Candida strains were obtained from hospitalized patients with nosocomial infection.
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Temel Bulgular & Veri:Most of the species were isolated from urine (77.8%) followed by oropharynx (8.2%), blood stream (6.1%), drain (6.1%), peritoneum (0.9%) and cerebrospinal fluid specimens (0.9%).
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Sonuç & Katkı:The resistance to miconazole, econazole and ketoconazole was higher at 18.8%, 15.8% and 23.6% respectively.
🔬Tür:Araştırma Makalesi
📍Kapsam:2000 Verileri
⚙️Değişkenler:Nosocomial fungal infections · antifungal susceptibility · ATB fungus

Özet

From January 1999 through April 2000, 208 Candida strains were obtained from hospitalized patients with nosocomial infection. Most of the species were isolated from urine (77.8%) followed by oropharynx (8.2%), blood stream (6.1%), drain (6.1%), peritoneum (0.9%) and cerebrospinal fluid specimens (0.9%). The distribution of the species obtained was Candida albicans (75.4%), C. glabrata (8.2%), C. tropicalis (4.8%), C. kefyr (3.4%), C. parapsilosis (2.5%), C. lusitaniae (1.9%), C. famata (1.4%), C. krusei (1.4%), and C. guilliermondii (1%). The antifungal susceptibility of the isolates to 5-fluorocytosine (5FCU), amphotericin B (AMP), nystatin (NYS), econazole (ECO), miconazole (MIC) and ketoconazole (KET) was tested by means of the ATB fungus method ((bioMerieux sa Marcy-l'Etoile/France). All the isolates were susceptible to amphotericin B, though a small number of in vitro resistant isolates were observed against nystatin and 5-fluorocytosine (3.4%). The resistance to miconazole, econazole and ketoconazole was higher at 18.8%, 15.8% and 23.6% respectively.

Abstract

From January 1999 through April 2000, 208 Candida strains were obtained from hospitalized patients with nosocomial infection. Most of the species were isolated from urine (77.8%) followed by oropharynx (8.2%), blood stream (6.1%), drain (6.1%), peritoneum (0.9%) and cerebrospinal fluid specimens (0.9%). The distribution of the species obtained was Candida albicans (75.4%), C. glabrata (8.2%), C. tropicalis (4.8%), C. kefyr (3.4%), C. parapsilosis (2.5%), C. lusitaniae (1.9%), C. famata (1.4%), C. krusei (1.4%), and C. guilliermondii (1%). The antifungal susceptibility of the isolates to 5-fluorocytosine (5FCU), amphotericin B (AMP), nystatin (NYS), econazole (ECO), miconazole (MIC) and ketoconazole (KET) was tested by means of the ATB fungus method ((bioMerieux sa Marcy-l'Etoile/France). All the isolates were susceptible to amphotericin B, though a small number of in vitro resistant isolates were observed against nystatin and 5-fluorocytosine (3.4%). The resistance to miconazole, econazole and ketoconazole was higher at 18.8%, 15.8% and 23.6% respectively.

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Bu Makaleye Atıf Yap

FINDIK, D., TUNCER, İ. (2022). Nosocomial Fungal Infections in a Teaching Hospital in Turkey: Identification of the Pathogens and Their Antifungal Susceptibility Patterns. Turkish Journal of Medical Sciences, Cilt: 32 - Sayı: 1, 35–38. https://ajindex.com/articles/612235

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