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Dergiler / Turkish Journal of Medical Sciences / 2013 / Cilt: 43 - Sayı: 3

Asymmetric dimethylarginine levels in allergic rhinitis and nasal polyposis

Tayfun APUHAN
Mehmet TOSUN
Sayfa
455–458
Yayın Tarihi
2022-11-05
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Conclusion: In the present study, lower ADMA levels were found in the AR and NP groups.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Asymmetric dimethylarginine (ADMA) is the major endogenous inhibitor of nitric oxide synthase.
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Temel Bulgular & Veri:Materials and methods: A total of 29 AR patients, 21 NP patients, and 30 healthy subjects to be used as a control group were enrolled in the study.
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Sonuç & Katkı:Conclusion: In the present study, lower ADMA levels were found in the AR and NP groups.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Key words: Asymmetric dimethylarginine · allergic rhinitis · nasal polyposis

Özet

Asymmetric dimethylarginine (ADMA) is the major endogenous inhibitor of nitric oxide synthase. We aimed to investigate the ADMA levels in allergic rhinitis (AR) and nasal polyposis (NP). Materials and methods: A total of 29 AR patients, 21 NP patients, and 30 healthy subjects to be used as a control group were enrolled in the study. ADMA was measured in the AR, NP, and control groups with enzyme-linked immunosorbent assay. Any patients or control subjects with coronary artery disease, renal failure, diabetes mellitus, or hypertension were excluded from the study. Results: The mean ADMA serum concentration was 0.52 ± 0.08 µmol/L in the AR group, 0.62 ± 0.10 µmol/L in the NP group, and 0.67 ± 0.09 µmol/L in the control group. The ADMA serum concentration in the AR group was significantly lower than in the control group (P < 0.001). Considered together, the NP and AR groups had ADMA levels that were significantly lower than in the control group (P < 0.001). Conclusion: In the present study, lower ADMA levels were found in the AR and NP groups.

Abstract

Asymmetric dimethylarginine (ADMA) is the major endogenous inhibitor of nitric oxide synthase. We aimed to investigate the ADMA levels in allergic rhinitis (AR) and nasal polyposis (NP). Materials and methods: A total of 29 AR patients, 21 NP patients, and 30 healthy subjects to be used as a control group were enrolled in the study. ADMA was measured in the AR, NP, and control groups with enzyme-linked immunosorbent assay. Any patients or control subjects with coronary artery disease, renal failure, diabetes mellitus, or hypertension were excluded from the study. Results: The mean ADMA serum concentration was 0.52 ± 0.08 µmol/L in the AR group, 0.62 ± 0.10 µmol/L in the NP group, and 0.67 ± 0.09 µmol/L in the control group. The ADMA serum concentration in the AR group was significantly lower than in the control group (P < 0.001). Considered together, the NP and AR groups had ADMA levels that were significantly lower than in the control group (P < 0.001). Conclusion: In the present study, lower ADMA levels were found in the AR and NP groups.

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Bu Makaleye Atıf Yap

APUHAN, T., TOSUN, M. (2022). Asymmetric dimethylarginine levels in allergic rhinitis and nasal polyposis. Turkish Journal of Medical Sciences, Cilt: 43 - Sayı: 3, 455–458. https://ajindex.com/articles/611056

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Kaynakça (11)

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